Parcourir par tags

Tous les tags » nanotechnologies » Nanoparticules (RSS)
ASTM E2535 - Standard Guide for Handling Unbound Engineered Nanoscale Particles in Occupational Settings
This guide is intended for use by entities involved in the handling of UNP in occupational settings. This guide covers handling principles and techniques that may be applied, as appropriate, to the variety of UNP materials and handling settings. These settings include research and development activities, material manufacturing, and material use and processing. This guide may also be used by entities that receive materials or articles containing or comprising nanoscale particles fixed upon or within a matrix (that is, bound nanoscale particles), but whose own processes or use may reasonably be expected...
Literature study on the uses and risks of nanomaterials as pigments in the European Union
This report provides a review on the safe use of nano-sized pigments when used by professionals, workers or consumers. Extensive literature searches were carried out in combination with analyses of data from national nano-inventories to capture the current state of play. The report provides a list of nano-sized pigments currently identified on the EU market and discusses potential risks arising from their use in paints, coatings, printer toner cartridges, personal care products, tattooes as well as other potential uses of nanopigments. Data for hazard and risk assessment are not available for the...
A Review of Workplace Risk Management Measures for Nanomaterials to Mitigate Inhalation and Dermal Exposure
This review describes an evaluation of the effectiveness of Risk Management Measures (RMM) for nanomaterials in the workplace. Our aim was to review the effectiveness of workplace RMM for nanomaterials and to determine whether established effectiveness values of conventional chemical substances applied for modelling purposes should be adopted or revised based on available evidence. A literature review was conducted to collate nano-specific data on workplace RMM. Besides the quantitative efficacy values, the library was populated with important covariables such as the study design, measurement type...
WHO Guidelines to Protect Workers from Nanomaterials
The term nanomaterials refers to materials that have at least one dimension (height, width or length) that is smaller than 100 nanometres (10−7 metre), which is about the size of a virus particle. This particular size dimension represents a major characteristic of manufactured nanomaterials (MNMs). The unique properties of MNMs may result in highly desirable behaviour leading to such varying applications as better paints, better drugs and faster electronics. However, for the same reason, MNMs may also present health hazards that differ from those of the substance in bulk form, and may require...
Activation des éosinophiles humains par des nanoparticules
L'économie du Canada, comme celle de bien d'autres pays industrialisés, bénéficie du développement des nanotechnologies dont le fort potentiel peut être exploité dans plusieurs secteurs industriels. Un nombre croissant d'entreprises québécoises de production de nanoparticules (NP) est d'ailleurs déjà implanté et tout porte à croire que d'autres emboîteront le pas dans les années à venir. Ce faisant, non seulement le nombre de travailleurs œuvrant dans la fabrication...
Workplace exposure and release of ultrafine particles during atmospheric plasma spraying in the ceramic industry
Atmospheric plasma spraying (APS) is a frequently used technique to produce enhanced-property coatings for different materials in the ceramic industry. This work aimed to characterise and quantify the impact of APS on workplace exposure to airborne particles, with a focus on ultrafine particles (UFPs, < 100 nm) and nanoparticles (< 50 nm). Particle number, mass concentrations, alveolar lung deposited surface area concentration, and size distributions, in the range 10 nm–20 μm were simultaneously monitored at the emission source, in the potential worker breathing zone, and in outdoor...
Challenges on the toxicological predictions of engineered nanoparticles
The perceived enormous potential of nanotechnology in contributing to sustainable innovation has led to the growth of investments into new industrial applications and consumer products. However, the lack of tools that are needed to generate early knowledge about the potential adverse effects, combined with the uncertainties regarding the health and safety risks of engineered nanoparticles (ENPs), are a potential threat to the acceptability by society of the nanotechnology innovations, due to the rising societal concerns that are based on generic worries. In order to tackle these issues, it has...
Évaluation de méthodes de prélèvement et de caractérisation de nanomatériaux manufacturés dans l'air et sur des surfaces des milieux de travail
La surveillance des niveaux de contamination de l'air par des nanomatériaux manufacturés (NMM) est une démarche complexe qui présente plusieurs incertitudes et limites notamment : la présence simultanée de particules de dimensions nanométriques qui ne sont pas des NMM, l'absence d'instruments validés permettant une mesure en zone respiratoire et la multiplicité des indicateurs à apprécier. Certains organismes, dont l'Institut national de recherche et de sécurité (INRS) en France et l'Institut...
Exposure to metal oxide nanoparticles administered at occupationally relevant doses induces pulmonary effects in mice
In spite of the great promises that the development of nanotechnologies can offer, concerns regarding potential adverse health effects of occupational exposure to nanoparticle (NP) is raised. We recently identified metal oxide NP in lung tissue sections of welders, located inside macrophages infiltrated in fibrous regions. This suggests a role of these NP in the lung alterations observed in welders. We therefore designed a study aimed to investigate the pulmonary effects, in mice, of repeated exposure to NP administered at occupationally relevant doses. We therefore chose four metal oxide NPs representative...
Refinement of the Nanoparticle Emission Assessment Technique into the Nanomaterial Exposure Assessment Technique (NEAT 2.0)
Engineered nanomaterial emission and exposure characterization studies have been completed at more than 60 different facilities by the National Institute for Occupational Safety and Health (NIOSH). These experiences have provided NIOSH the opportunity to refine an earlier published technique, the Nanoparticle Emission Assessment Technique (NEAT 1.0), into a more comprehensive technique for assessing worker and workplace exposures to engineered nanomaterials. This change is reflected in the new name Nanomaterial Exposure Assessment Technique (NEAT 2.0) which distinguishes it from NEAT 1.0. NEAT...
Occupational dermal exposure to nanoparticles and nano-enabled products
Part 2, exploration of exposure processes and methods of assessment In the first of a series of two papers (Larese Filon et al., 2016), we focused our attention on identifying conditions or situations, i.e. a combination of nanoparticle physico-chemical properties, skin barrier integrity, and occupations with high prevalence of skin disease, which deserve further investigation. This second paper focuses on the broad question of dermal exposure assessment to nanoparticles and attempts to give an overview of the mechanisms of occupational dermal exposure to nanoparticles and nano-enabled products...
Occupational dermal exposure to nanoparticles and nano-enabled products
Part I - Factors affecting skin absorption The paper reviews and critically assesses the evidence on the relevance of various skin uptake pathways for engineered nanoparticles, nano-objects, their agglomerates and aggregates (NOAA). It focuses especially in occupational settings, in the context of nanotoxicology, risk assessment, occupational medicine, medical/epidemiological surveillance efforts, and the development of relevant exposure assessment strategies. Skin uptake of nanoparticles is presented in the context of local and systemic health effects, especially contact dermatitis, skin barrier...
Control banding tools for occupational exposure assessment of nanomaterials
Ready for use in a regulatory context? The development, production and application of engineered nanomaterials are becoming more and more widespread. Because researchers, developers and industrial workers are the first in line to be exposed to potentially hazardous nanomaterials, appropriate occupational exposure assessment is a key area of concern. Therefore, a number of Control Banding (CB)-based tools have been developed in order to assess and manage the potential risks associated with occupational exposure to nanomaterials.In this paper we provide a comparative analysis of different nanomaterial...
Dioxyde de titane nanométrique
De la nécessité d'une valeur limite d'exposition professionnelle Dès 2005, l'INRS a souligné la nécessité d'engager une réflexion relative aux valeurs limites d'exposition professionnelle en lien avec les nanomatériaux en raison de leurs propriétés toxicologiques particulières. Cet article propose, à partir de l'analyse de travaux initiés depuis en Europe, au Japon et aux États-Unis, une valeur limite d'exposition professionnelle pour le dioxyde de titane nanométrique...
Summary of work undertaken to assess workplace exposure and control measures during the manufacture and handling of engineered nanomaterials
The aim of this research was to develop an improved understanding of the UK nanomaterial industry and of worker exposure to engineered nanomaterials, through visits to companies manufacturing or using these materials. The visits were undertaken to assess exposure to airborne nanomaterials and to assess the effectiveness of the controls used to reduce exposure. Source: http://www.hse.gov.uk/research/rrhtm/rr1068.htm
Nanomatériaux – Guide de bonnes pratiques favorisant la gestion des risques en milieu de travail
2e édition Dans l’intention de soutenir le développement sécuritaire des nanotechnologies au Québec, le présent guide souhaite rassembler les connaissances scientifiques actuelles sur l’identification des dangers, les stratégies d’évaluation du niveau de nanomatériaux retrouvés dans différents milieux de travail, l’évaluation des risques et finalement l’application de différentes approches à la gestion des risques. Ce guide, dont l’utilisation optimale requiert un minimum...
Industrial Production and Professional Application of Manufactured Nanomaterials-Enabled End Products in Dutch Industries: Potential for Exposure
Background: In order to make full use of the opportunities while responsibly managing the risks of working with manufactured nanomaterials (MNM), we need to gain insight into the potential level of exposure to MNM in the industry. Therefore, the goal of this study was to obtain an overview of the potential MNM exposure scenarios within relevant industrial sectors, applied exposure controls, and number of workers potentially exposed to MNM in Dutch industrial sectors producing and applying MNM-enabled end products in the Netherlands. Methods : A survey was conducted in three phases: (i) identification...
FIOH’s Nanodevice project is a European success story
The European Commission has labelled the NANODEVICE project, co-ordinated by the Finnish Institute of Occupational Health (FIOH), a success story. The project produced affordable measuring devices for determining the concentrations of nanoparticles in the air. The new NANOSOLUTIONS project is another potential success story, with its aim to create a completely new way of evaluating the health hazards of industrial nanoparticles Source : http://www.ttl.fi/en/press/Pages/pressrelease15_2013.aspx
Dustiness of Fine and Nanoscale Powders
Dustiness may be defined as the propensity of a powder to form airborne dust by a prescribed mechanical stimulus; dustiness testing is typically intended to replicate mechanisms of dust generation encountered in workplaces. A novel dustiness testing device, developed for pharmaceutical application, was evaluated in the dustiness investigation of 27 fine and nanoscale powders. The device efficiently dispersed small (mg) quantities of a wide variety of fine and nanoscale powders, into a small sampling chamber. Measurements consisted of gravimetrically determined total and respirable dustiness. The...
New study of nanoparticle skin penetration
As engineered nanoparticles (ENPs) become increasingly common in consumer products and the environment, concern over their possible effects on human health also rises. There is concern over the possible penetration of human skin by ENPs. "However, the evidence whether nanoparticles can infiltrate into underlying tissues is conflicting . . . clarification of the issue is essential. . .." With this in mind, Christopher. S.J. Campbell of Mango Business Solutions, L. Roderigo Contreras-Rojas, M. Begona Delgado-Charro, and Richard H. Guy, of the University of Bath Department of Pharmacy &...
A Road Map Toward a Globally Harmonized Approach for Occupational Health Surveillance and Epidemiology in Nanomaterial Workers
Objective: Few epidemiological studies have addressed the health of workers exposed to novel manufactured nanomaterials. The small current workforce will necessitate pooling international cohorts. Method : A road map was defined for a globally harmonized framework for the careful choice of materials, exposure characterization, identification of study populations, definition of health endpoints, evaluation of appropriateness of study designs, data collection and analysis, and interpretation of the results.Results: We propose a road map to reach global consensus on these issues. The proposed strategy...
Four types of inorganic nanoparticles stimulate the inflammatory reaction in brain microglia and damage neurons in vitro
Once nanoparticles enter the central nervous system (CNS), they immediately encounter a complex environment of resident microglial immune cell and neurons. In the present study, NPs of 20–60 nm in diameter (SiO2-NPs, TiO2-NPs, HAP-NPs and Fe3O4-NPs) were evaluated for their ability to induce microglia-mediated neurodegeneration. The microglia were directly exposed to NPs. The results showed that both TiO2-NPs and HAP-NPs induced significant iNOS expression, resulting in NO release from the microglia. The expression levels of MCP-1 and MIP-1α were also upregulated. These activation effects...
Nanotechnology-theme in new Barents Newsletter
Research Professor Harri Alenius comments on his Editorial in the latest Barents Newsletter: "Nanotechnologies using Engineered nanomaterials (ENMs) are envisaged to become the cornerstone for a number of industrial sectors, from micro-electronics, materials, paper, textile, to energy and cosmetics, industries which are all capable of incorporating some nano-scale-enabled properties into their goods. However, the well-documented issues regarding the safety of ENM have given rise to increasing concerns not only for regulators and the general public but also for industries. A clear understanding...
Risk perception and risk communication with regard to nanomaterials in the workplace
Manufactured nanomaterials can bring huge benefits to society but there are concerns about their health and environmental hazards. This literature review shows that there are also serious gaps in the awareness of the potential risks involved in handling manufactured nanomaterials in the workplace, and serious shortcomings in the way that those risks are communicated to the workplace. Effective, transparent, balanced and open risk communication strategies tailored to workplaces are needed to help employers and workers make informed decisions and put adequate prevention measures in place. Source...
Risks and Control of Nanomaterials
Editorial / Trevor Ogden. In this issue we bring together 12 articles on nanomaterials and approaches to risk control. The issue originated with the conference held in April (2011) by the Institut National de Recherche et de Sécurité (INRS) in Nancy, France, on risks associated with nanoparticles and nanomaterials. Topics included measurement and control process design, occupational toxicology, protection, epidemiology, assessment and management of risk of nanoparticles. Source : http://annhyg.oxfordjournals.org/content/56/5/489.full
Plus de Messages Page suivante »

Abonnement courriel

Messages récents

Catégories

Mots-Clés (Tags)

Blogoliste

Archives