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Summary of evidence – Solvent-based hydrophobic coatings and risks for acute respiratory toxicity
Water repellent coatings are increasingly used by different industries to reduce water and dirt sticking to surfaces. The coatings can be applied by processes that minimise the risk that operators inhale the product but there is evidence that some products are applied by spraying, creating an inhalable mist. This review examined evidence about these coatings and whether lung disease occurs when applied by spraying. Scientific studies on the hazardous properties of these products, and clinical studies reporting lung disease in people using them, were considered. A consistent finding was that some...
Neurotoxicity associated with exposure to 1-bromopropane in golf-club cleansing workers
BACKGROUND: 1-Bromopropane (1-BP) is an alternative to ozone-depleting solvent that is used in degreasing, dry cleaning, spray adhesives, and aerosol solvents. Occupational exposure to 1-BP is associated with adverse peripheral sensory, motor, and central nervous system (CNS) effects. We report our Health Hazard and Medical Evaluation of 6 patients with neurotoxicity associated with occupational exposure to 1-BP. Case series and environmental evaluation. Six workers, 1 male and 5 female, were exposed to high ambient 1-BP concentrations while employed in a golf club cleaning factory. 1-BP was identified...
Fatalities due to dichloromethane in paint strippers: A continuing problem
Background Exposure to dichloromethane (DCM or methylene chloride - CH2Cl2) in paint strippers continues to be an avoidable source of morbidity and mortality. DCM has been under regulatory scrutiny by occupational and consumer product agencies since the identification of its carcinogenicity in the mid-1980s. Methods We investigated two independent workplace incidents that resulted in three cases of DCM intoxication from paint stripper use. Results Each incident investigated resulted in a fatality. A third worker suffered obtundation requiring hospitalization and intubation. Conclusions The continued...
Health assessment for trichloroethylene
Ce document de l’Environmental Protection Agency (EPA) des États-Unis annonce l'achèvement de l'évaluation d’impact sur la santé du polluant chimique trichloréthylène (TCE) et l’incorporation de l'évaluation dans l'Integrated Risk Information System (IRIS). La base de données IRIS fournit de l'information scientifique pour les décideurs de tous les niveaux. Le trichloréthylène est un solvant chloré largement utilisé et maintenant officiellement classé comme un...
Polyneuropathy or encephalopathy caused by organic solvents, in isolation or in mixtures
The second edition of the Occupational Diseases Report 1317 enables quality-assured processing in cases with a suspicion of work-induced damage to the nervous system by organic solvents on the basis of technical and medical expert knowledge. In the first part, there is technical information with specific information on solvents and mixtures whose neuro-toxicity has been proved according to the current level of knowledge. The Report contains overviews on the incidence of the substances in various industries as well as substance dossiers with chemical and physical data, limit values and absorption...

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