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Neurotoxicity associated with exposure to 1-bromopropane in golf-club cleansing workers
BACKGROUND: 1-Bromopropane (1-BP) is an alternative to ozone-depleting solvent that is used in degreasing, dry cleaning, spray adhesives, and aerosol solvents. Occupational exposure to 1-BP is associated with adverse peripheral sensory, motor, and central nervous system (CNS) effects. We report our Health Hazard and Medical Evaluation of 6 patients with neurotoxicity associated with occupational exposure to 1-BP. Case series and environmental evaluation. Six workers, 1 male and 5 female, were exposed to high ambient 1-BP concentrations while employed in a golf club cleaning factory. 1-BP was identified...
Filling the Knowledge Gaps for Safe Nanotechnology in the Workplace
A Progress Report from the NIOSH Nanotechnology Research Center, 2004–2011. This 2012 update presents the program accomplishments of the NTRC from its inception in 2004 through 2011. It includes an analysis of the progress made toward accomplishing the goals and objectives of the NIOSH Strategic Plan for Nanotechnology Research and toward addressing the goals and research needs identified in the U.S. National Nanotechnology Initiative (NNI) Environmental, Health, and Safety (EHS) research strategy. Source :
Neurotoxic exposures and effects: Gender and sex matter! Hänninen Lecture 2011
Donna Mergler, cofondatrice du CINBIOSE, a écrit un article portant sur l'importance du genre et du sexe dans les recherches en neurotoxicologie de l'environnement et du travail. Trop peu de recherches en tiennent compte et ne différencient pas clairement le genre et le sexe. C'est pourquoi l'auteure souligne que c'est un impératif d'en tenir compte! Source : Mergler, D. Neurotoxic exposures and effects: Gender and sex matter! Ha¨nninen Lecture 2011. Neurotoxicology. 2012.
Potential developmental neurotoxicity of pesticides used in Europe
Pesticides used in agriculture are designed to protect crops against unwanted species, such as weeds, insects, and fungus. Many compounds target the nervous system of insect pests. Because of the similarity in brain biochemistry, such pesticides may also be neurotoxic to humans. Concerns have been raised that the developing brain may be particularly vulnerable to adverse effects of neurotoxic pesticides. Current requirements for safety testing do not include developmental neurotoxicity. We therefore undertook a systematic evaluation of published evidence on neurotoxicity of pesticides in current...

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