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Occupational use of high-level disinfectants and fecundity among nurses
Objective: This study aimed to examine the relationship between occupational use of high-level disinfectants (HLD) and fecundity among female nurses. Methods: Women currently employed outside the home and trying to get pregnant (N=1739) in the Nurses' Health Study 3 cohort (2010–2014) were included in this analysis. Occupational exposure to HLD used to disinfect medical instruments and use of protective equipment (PE) was self-reported on the baseline questionnaire. Every six months thereafter women reported the duration of their ongoing pregnancy attempt. Multivariable accelerated failure...
Reproductive Health Risks Associated With Occupational Exposures to Antineoplastic Drugs in Health Care Settings
A Review of the Evidence Objectives: Antineoplastic drugs are known reproductive and developmental toxicants. Our objective was to review the existing literature of reproductive health risks to workers who handle antineoplastic drugs. Methods: A structured literature review of 18 peer-reviewed, English language publications of occupational exposure and reproductive outcomes was performed. Results: Although effect sizes varied with study size and population, occupational exposure to antineoplastic drugs seems to raise the risk of both congenital malformations and miscarriage. Studies of infertility...
Two reproduction toxicity evaluations – Chloramphenicol and indium and its compounds
The Health Council of the Netherlands has reviewed chloramphenicol and indium compounds. Indium is used in bearings for cars and aircrafts, in solders and low-melting alloys, and in nuclear reactor control rods. Indium and its compounds, including indium antimonide (InSb), indium arsenide (InAs), and indium phosphide (InP), find application in semiconductor devices, transistors, and transistor materials. Indium oxide is used for colouring glass. Indium sulphate is used in electroplating, and radioisotopes of indium and indium compounds (including indium trichloride) are employed in the treatment...

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