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Évolution de l’exposition professionnelle aux solvants oxygénés, pétroliers et chlorés en France entre 1999 et 2013
Résultats du programme Matgéné L'évolution de l'exposition professionnelle aux solvants oxygénés, pétroliers et chlorés entre 1999 et 2013 en France est présentée selon le sexe et le secteur d'activité. Les expositions sont évaluées par les matrices emplois-expositions du programme Matgéné. Les données de population issues des recensements de 1999, 2007 et 2013 sont croisées avec les matrices pour estimer les prévalences d'exposition sur les trois années...
Case-control investigation of occupational exposure to chlorinated solvents and non-Hodgkin’s lymphoma
Objectives: Although many studies have investigated the association between trichloroethylene (TCE) exposure and non-Hodgkin's lymphoma (NHL), less is known about other chlorinated solvents. We extended our previous analysis of occupational TCE exposure in a multicentre population-based case-control study of NHL to investigate associations with five additional chlorinated solvents: 1,1,1,-trichloroethane, carbon tetrachloride, chloroform, methylene chloride and perchloroethylene. Methods: Cases (n=1189) and controls (n=982) provided detailed information on their occupational histories and workplace...
Occupational exposures to solvents and metals are associated with fixed airflow obstruction
Our study is the first to investigate the associations between exposures to solvents and metals using lifetime work history calendars and fixed airflow obstruction (AO). We have shown that increasing cumulative exposure-unit years to chlorinated solvents is associated with fixed AO. We found that women were at increased risk of fixed AO with increasing cumulative exposed-unit-years to chlorinated solvents but not men. Source: Alif SM, Dharmage SC, Benke G, Dennekamp M, Burgess JL, Perret, Lodge CJ, Morrison S, Johns DP?, Giles GG, Gurrin LC, Thomas PS, Hopper JL, Wood-Baker R, Thompson BR, Feather...
Exposure to chlorinated solvents and lung cancer
Results of the ICARE study Objective: To investigate the role of occupational exposure to chlorinated solvents in lung cancer aetiology. Methods: ICARE (Investigation of occupational and environmental CAuses of REspiratory cancers) is a French, multicentre, population-based, case–control study. Information on the lifelong work history of 2926 cases and 3555 controls was collected using standardised questionnaires. Occupational exposures were assessed using job-exposure matrices for five chlorinated solvents. Solvents were studied separately and in combinations. ORs were computed using unconditional...

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