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Exposure-response relationships for silicosis and its progression in industrial sand workers
Objectives: This study aimed to characterize the relationship between radiographic silicosis and exposure to respirable quartz and determine how exposure affects disease progression. Methods: Surveillance chest radiographs from a cohort of 1902 workers were examined to identify 67 cases of radiographic silicosis and 167 matched controls. Exposures were estimated by linking work histories to a job exposure matrix (JEM) based on samples collected by the participating companies and historical estimates. Conditional logistic regression was used to examine exposure-response relationships. Sequential...
Surveillance for Silicosis
Michigan and New Jersey, 2003–2011 CDC's National Institute for Occupational Safety and Health (NIOSH), state health departments, and other state entities maintain a state-based surveillance program of confirmed silicosis cases. Data on confirmed cases are collected and compiled by state entities and submitted to CDC. This report summarizes information for cases of silicosis that were reported to CDC for 2003–2011 by Michigan and New Jersey, the only states that continue to provide data voluntarily to NIOSH. Source: http://www.cdc.gov/mmwr/volumes/63/wr/mm6355a7.htm
Bronchoalveolar Lavage Fluid microRNA-146a: A Biomarker of Disease Severity and Pulmonary Function in Patients With Silicosis
Objective: To examine the impact of microRNA-146a (miR-146a) on pulmonary function and disease severity in silicosis patients. Methods: Twenty-nine silicosis patients and six observation subjects were recruited. MiR-146a expression level was detected by qRT-PCR, and pulmonary function was assessed with a spirometer. Results: MiR-146a expression level was higher in silicosis patients than in observation subjects, and the probability of suffering from silicosis increased with increasing miR-146a level. MiR-146a was associated with the severity of silicosis. As the miR-146a increased, the probability...
Surveillance for Silicosis
Michigan and New Jersey, 2003-2010 CDC's National Institute for Occupational Safety and Health (NIOSH), state health departments, and other state entities maintain a state-based surveillance program of confirmed silicosis cases. Data on confirmed cases are collected and compiled by state entities and submitted to CDC. This report summarizes information for cases of silicosis that were reported to CDC for 2003-2010. The data for this report were final as of December 31, 2010. Data are presented in tabular form on the prevalence of silicosis, the number of cases and the distribution of cases...
Silicosis Update
Silicosis is a potentially fatal but preventable occupational lung disease caused by inhaling respirable particles containing crystalline silicon dioxide (silica). Quartz, a type of crystalline silica, is the second most abundant mineral in the earth's crust and workers across a wide range of occupations and industries are exposed to silica-containing dusts. The risks, causes, and prevention of this avoidable disease have been known for decades. There is no cure for silicosis and only symptomatic treatment is available, including lung transplantation for the most severe cases. New national...
Worker Exposure to Silica during Countertop Manufacturing, Finishing and Installation
The Occupational Safety and Health Administration (OSHA) and the National Institute for Occupational Safety and Health (NIOSH) have identified exposure to silica as a health hazard to workers involved in manufacturing, finishing and installing natural and manufactured stone countertop products, both in fabrication shops and during in-home finishing/installation. This hazard can be mitigated with simple and effective dust controls in most countertop operations. Source: https://www.osha.gov/Publications/OSHA3768.pdf
Silicosis Mortality Trends and New Exposures to Respirable Crystalline Silica
United States, 2001–2010 Silicosis is a preventable occupational lung disease caused by the inhalation of respirable crystalline silica dust and can progress to respiratory failure and death (1). No effective specific treatment for silicosis is available; patients are provided supportive care, and some patients may be considered for lung transplantation. Chronic silicosis can develop or progress even after occupational exposure has ceased (1). The number of deaths from silicosis declined from 1,065 in 1968 to 165 in 2004 (2). Hazardous occupational exposures to silica dust have long been...
Outbreak of silicosis in Spanish quartz conglomerate workers
Objectives: To describe the epidemiological and clinical characteristics of an outbreak of occupational silicosis and the associated working conditions. Methods: Cases were defined as men working in the stone cutting, shaping, and finishing industry in the province of Cádiz, diagnosed with silicosis between July 2009 and May 2012, and were identified and diagnosed by the department of pulmonology of the University Hospital of Puerto Real (Cádiz). A census of workplaces using quartz conglomerates was carried out to determine total numbers of potentially exposed workers. A patient telephone...
Silica Hazards from Engineered Stone Countertops
A new engineered stone countertop product known as “quartz surfacing,” was created in the late 1980s by combining quartz aggregate with resins to create a product for use in home building and home improvement. Manufacturing of this material, including products such as CaesarStone™, Silestone™, Zodiaq™, or Cambria™ is a fast growing industry. First made in Israel and Spain, production of these materials has grown world-wide, driving quartz slab imports to the U.S. up 63% between 2011 and 2012 and 48% between April 2012 and April 2013 (Schwartzkopf 2013, StatWatch...
New website on site work and silica
The US based Center for Construction Research and Training (CPWR), has launched a 'Work safely with silica' website. CPWR, an organisation working closely with US construction unions, says as well as giving details of US silica regulation and official research, the new resource includes other research, articles, and training materials, as well as responses to frequently asked questions. Central features of the new site include a 'Know the hazard' section, geared for anyone interested in learning more about why silica is hazardous, the risk, who's at risk, the health effects...
Asbestos and Other Occupational Lung Diseases in New Zealand :2010 Annual Report
Rapport sur les maladies pulmonaires reliées à l'amiante et à d'autres substances en Nouvelle-Zélande. Source : http://www.osh.govt.nz/publications/booklets/asbestos-report-2010/report-2010.pdf
Health surveillance in silica exposed workers
There is uncertainty in Great Britain (GB) about what constitutes appropriate health surveillance for silica-exposed workers, despite evidence that new cases of silicosis are occurring. The main objectives of this report are: 1) To identify existing recommendations for health surveillance for silica-exposed workers. 2) To assess the evidence base for these recommendations and other relevant evidence in the scientific literature. 3) To make recommendations for a standard. Source : http://news.hse.gov.uk/2010/11/15/rr827-health-surveillance-in-silica-exposed-workers/
Controlling dust during the refurbishment and extension of occupied premises
All RCS is hazardous and can cause silicosis and other serious lung diseases such as chronic obstructive pulmonary disease or lung cancer leading to permanent disability or early death. http://www.hse.gov.uk/construction/healthrisks/coh15.pdf?ebul=hsegen/24-nov-2008&cr=17

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