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Occupational exposure to organic solvents and risk of male breast cancer
A European multicenter case-control study Objectives: The etiology of male breast cancer (MBC) is largely unknown but a causal role of exposure to organic solvents has been suggested. Previous studies on occupational risk factors of breast cancer were often restricted to women who are frequently exposed to lower levels and at a lower frequency than men. We investigated the association between MBC and occupational exposure to petroleum and oxygenated and chlorinated solvents in a multicenter case–control study of rare cancers in Europe. Methods: The study included 104 MBC cases and 1901 controls...
State of the evidence 2017: an update on the connection between breast cancer and the environment
Singly and in combination, these toxicants may have contributed significantly to the increasing rates of breast cancer observed over the past several decades. Exposures early in development from gestation through adolescence and early adulthood are particularly of concern as they re-shape the program of genetic, epigenetic and physiological processes in the developing mammary system, leading to an increased risk for developing breast cancer. In the 8 years since we last published a comprehensive review of the relevant literature, hundreds of new papers have appeared supporting this link, and in...
Breast cancer incidence among female flight attendants
Exposure–response analyses In a cohort of 6093 female flight attendants, breast cancer incidence was not associated with cumulative exposure to cosmic radiation or two metrics of circadian rhythm disruption. Positive exposure–response relations were observed only in the small subset of the cohort with parity of three or more. Cautious interpretation of the findings in women with high parity is warranted. Source: Pinkerton LE, Hein MJ, Anderson JL, Little MP, Sigurdson AJ, Schubauer-Berigan MK. Scand J Work Environ Health , 2016.
The Breast Cancer Fund: Working Women and Breast Cancer
The State of the Evidence Based on the current evidence, action to reduce workplace exposures linked to breast cancer is imperative. The Breast Cancer Fund has spent nearly 15 years translating the science that links environmental exposures to breast cancer, and advocating for change. In the past several years, it has become increasingly evident that the workplace may be a substantive source of many of these exposures and of the resulting risk for breast cancer. Source:
Exposition professionnelle aux solvants organiques et cancers du sein chez l’homme et la femme
De nouveaux résultats renforcent les hypothèses sur des facteurs de risque environnementaux En France, chaque année, plus de 53 000 nouveaux cas et plus de 11 000 décès par cancer du sein sont recensés. Les facteurs de risque connus ne permettent d'expliquer qu'une minorité des cancers du sein, dans un contexte d'augmentation de l'incidence de cette maladie dans les pays industrialisés. D'autres facteurs de risque, notamment des expositions environnementales ou professionnelles, sont suspectés mais restent moins...
Occupational Exposure to Ionizing Radiation and Risk of Breast Cancer in Western Australia
Objective: To evaluate current breast cancer risk due to occupational exposure to ionizing radiation. Methods: We analyzed data from the Western Australian population-based Breast Cancer Employment and Environment Study. The Breast Cancer Employment and Environment Study included 1205 cases with incident breast cancer during 2009–2011 and 1789 controls. Age-adjusted odds ratios (ORs) were estimated with logistic regression models. Results: There was a weak, not statistically significant association between breast cancer and occupational exposure to ionizing radiation (OR = 1.16; 95% confidence...
Cancer du sein, professions et expositions professionnelles aux solvants organiques
Résultats de deux études épidémiologiques sur les cancers du sein chez l'homme et chez la femme Des causes professionnelles ont été évoquées à propos du cancer du sein. Nous avons étudié le risque du cancer du sein par profession et en fonction des expositions professionnelles aux solvants pétroliers et chlorés dont le rôle a été évoqué. Nous avons utilisé les données de deux études cas-témoins en population, dont l'une porte sur les cancers...

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