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Modelling of occupational exposure to inhalable nickel compounds
The aim of this study was to estimate average occupational exposure to inhalable nickel (Ni) using the German exposure database MEGA. This database contains 8052 personal measurements of Ni collected between 1990 and 2009 in adjunct with information on the measurement and workplace conditions. The median of all Ni concentrations was 9 μg/m3 and the 95th percentile was 460 μg/m3. We predicted geometric means (GMs) for welders and other occupations centered to 1999. Exposure to Ni in welders is strongly influenced by the welding process applied and the Ni content of the used welding...
Exposure to carcinogens in surface engineering
Supplementary report This report details work undertaken following HSE research published as RR963 Exposure to hexavalent chromium, nickel and cadmium compounds in the electroplating industry (Keen et al, 2013). This examined the use of biological monitoring (BM) in the surface engineering (electroplating) industry. The report examines the efficacy of gloves, the use of surfactants and local exhaust ventilation in chromium plating, and the potential for transfer of contaminants outside the workplace. Source: http://www.hse.gov.uk/research/rrhtm/rr1042.htm
Relationship Between Urinary Nickel and Methylation of p15, p16 in Workers Exposed to Nickel
Objective: The purpose of this study was to investigate the relationship between urinary nickel and methylation of p15, p16 in workers exposed to nickel. Methods: In this study, 165 nickel-exposed workers and 67 workers without exposure were recruited. The levels of urinary nickel were analyzed using dimethylglyoxime spectrophotometric method. Methylation–specific polymerase chain reaction was used to detect the methylation of p15 and p16. Results: The median concentration of urinary nickel in the exposed group (4.58 μg/L) was significantly higher than that in the control group (1.78 μg...
Exposure to hexavalent chromium, nickel and cadmium compounds in the electroplating industry - RR963
This research was conducted by HSE in partnership with the Surface Engineering Association (SEA). The aim was to investigate whether repeat Biological Monitoring (BM) over a period of time could be used to help drive sustainable improvements in exposure control. Fifty-three companies engaged in nickel, hexavalent chromium and/or cadmium electroplating were visited. An occupational hygiene assessment of relevant tasks and exposure controls was conducted at each visit. BM (post shift urine sampling) was used to quantitatively assess nickel, chromium and (where used) cadmium exposures. Other measurements...
Metals in the Lungs of Ontario Hardrock Miners
The objective of this study was to determine the concentration of nickel, cadmium, and lead in the autopsied lungs of 29 hardrock miners. It involved chemical analysis of the lungs, where each lung was divided horizontally into 3 sections and analyzed by an atomic absorption spectrophotometer equipped with a graphite furnace. The grand mean levels of nickel, cadmium, and lead were found to be 1.84, 1.74, and 2.75 μg/g of dry tissue, respectively. The effect of smoking was also examined. The ratios using the mean values between smoker and nonsmoker for nickel, cadmium, and lead were found to...
Unrecognized risks of nickel-related respiratory cancer among Canadian electrolysis workers
Objectives Nickel compounds, inclusive of water-soluble salts, have been classified as human carcinogens by the International Agency for Research on Cancer (IARC). Nickel producers have disputed the classification of soluble nickel compounds for three decades with reference to an alleged absence of excess respiratory cancer among Canadian nickel-exposed electrolysis workers. We evaluated historical data from two electrolytic refineries in Ontario, both included in prominent Canadian reports on occupational nickel-related cancer. Methods For Port Colborne nickel refinery (PCNR) and Copper Cliff...
A small survey of exposure to stainless steel welding fume
Specific aims and objectives for the project were to visit a representative group of workplaces carrying out welding of stainless steel, scoping the various control strategies proposed in COSHH Essentials for welding, hot work and allied processes. Source : http://news.hse.gov.uk/2010/01/26/rr770-a-small-survey-of-exposure-to-stainless-steel-welding-fume/?rss=Research
New Skin Disorder caused by Mobile Phones discovered
Doctors are being warned to be alert to a new allergic skin disorder, caused by mobile phones, according to the British Association of Dermatologists. A new phenomenon called "mobile phone dermatitis" has been discovered, in which people who spend long periods of time on their mobile phone develop an allergic reaction to the phone's nickel surface. The problem was identified in several published case reports of patients with unexplained rashes on their face and ear. Closer investigation revealed that the reaction was caused by nickel in the mobile phone handsets, where it is often...

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