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Protocole de mise au point des méthodes de prélèvement surfacique et d’analyse des substances chimiques sur les surfaces de travail
Ce guide décrit un protocole pour la mise au point et la validation des méthodes de prélèvement et d'analyse des substances chimiques présentes sur les surfaces de travail. Ce protocole peut être appliqué par tout laboratoire souhaitant mettre au point ses propres méthodes. Il est conforme aux exigences normatives et aux pratiques courantes sur le sujet. Ce protocole répond à plusieurs objectifs :  - permettre à tout laboratoire d’effectuer lui-même la mise au point d’une méthode, dans le respect...
ASTM E3193 - Standard Test Method for Measurement of Lead (Pb) in Dust by Wipe, Paint, and Soil by Flame Atomic Absorption Spectrophotometry (FAAS)
This test method covers the determination of lead (Pb) in dust by wipe, paint, and soil collected in and around buildings and related structures by flame atomic absorption spectrophotometry (FAAS) and is derived from Test Methods D4185 and E1613. Source: https://www.astm.org/Standards/E3193.htm
SysDEA: Systematic analysis of dermal exposure to hazardous chemical agents at the workplace
The overall objective of the SysDEA study is to generate scientific knowledge for improvement and standardization of measurement methods for dermal exposure to chemicals at the workplace. To this end, five different tasks (transfer, spreading, spraying, handling immersed objects, and handling contaminated objects) were performed with three different product types: a dusty powder (solids) and high viscosity (HV) and low viscosity (LV) liquids. The investigated exposure situations (product-task combinations) were: dumping powder, pouring LV and HV (transfer), rolling LV and HV (spreading), surface...
Évaluation de l'exposition aux produits chimiques par les prélèvements surfaciques
De nombreuses activités professionnelles génèrent des dépôts sur les surfaces et les objets. Cette pollution surfacique peut alors conduire à une contamination des travailleurs par passage percutané et par ingestion. Une étude a été conduite dans le but de proposer une méthodologie d'évaluation des polluants présents sur les surfaces de travail. Issue de travaux expérimentaux ayant permis d'identifier les paramètres influents, cette méthodologie est actuellement mise en oeuvre...
Measuring and controlling emissions from polymer filament desktop 3D printers
Affordable desktop 3D printers are being widely used in businesses, schools and colleges. Some of these printers use filaments to deposit polymer through a heated nozzle to build three dimensional objects. This type of desktop printer is generally unenclosed and some published studies have raised concerns that they may release potentially harmful fumes and particles. The scientific evidence base on exposures and potential health endpoints is being developed internationally. This report describes initial research in a laboratory setting to a) measure emissions of particulates and volatile organic...
Human exposure to uranium in South African gold mining areas using barber-based hair sampling
Uranium (U) measurements in water, soil, and food related to gold mining activities in populated areas in Gauteng Province, South Africa, suggest the possibility of exposure levels that may lead to adverse health consequences, including cancer. Theoretical considerations on pathways of human uptake of significant exposures are plausible, but few data on directly measured human exposure are available. A cross-sectional study was conducted using human measurements to compare U levels with other settings around the globe (based on literature review), to explore potential exposure variability within...
Halogenated flame retardants and organophosphate esters in the air of electronic waste recycling facilities
Evidence of high concentrations and multiple exposures Background: In response to a worldwide increase in production of electronic waste, the e-recycling industry is rapidly rowing. E-recycling workers are exposed to many potentially toxic contaminants, among which flame retardants (FRs), mainly suspected of being endocrine disruptors, are thought to be the most prevalent. Objective: To conduct an exposure assessment of four chemical groups of FRs in Canadian e-recycling facilities, and to identify the main cofactors of exposure. Methods: Personal air samples were collected over a workday for 85...
Caractérisation des émissions de bitume haute résistance au désenrobage (HRD) avec dope d'adhésivité
Produit de distillation du pétrole, le bitume est chauffé puis mélangé à de la matière minérale broyée (le granulat) pour former l'enrobé bitumineux qui est utilisé pour le pavage de la grande majorité des routes. Les gaz, vapeurs et particules émis lorsque le bitume ou l'enrobé est chauffé sont constitués d'un groupe complexe de composés chimiques réglementés sous le nom de fumées d'asphalte (ou de bitume), notamment dans le Règlement sur la...
NF EN 17199-3 - Mesurage du pouvoir de resuspension des matériaux en vrac contenant des nano-objets et leurs agrégats et agglomérats (NOAA) ou autres particules en fraction alvéolaire
Le présent document décrit la méthodologie permettant de mesurer le pouvoir de resuspension de matériaux en vrac contenant ou émettant des NOAA ou autres particules en fraction alvéolaire dans des conditions normalisées et reproductibles et spécifie, à cette fin, le but de la méthode de la chute continue. Le présent document spécifie le choix des instruments et dispositifs ainsi que les procédures de calcul et d'expression des résultats. Il fournit également des lignes directrices concernant...
Transformation du granit - Caractérisation et contrôle de la poussière de la silice émise par le polissage
La présente étude contribue à l'avancement des connaissances nécessaires pour déterminer des moyens d'élimination et de réduction à la source des poussières fines et ultrafines contenant de la silice cristalline et qui sont émises lors de la transformation du granit. L'élimination et la réduction à la source des émissions sont les moyens privilégiés pour assurer un environnement de travail sain et sécuritaire; l'utilisation des équipements de protection individuelle...
Assessment of Occupational Exposure to Organic Flame Retardants: A Systematic Review
Background: Flame retardants (FRs) are widespread in common goods, and workers in some industries can be exposed to high concentrations. Numerous studies describe occupational exposure to FRs, but the diversity of methods and of reported results renders their interpretation difficult for researchers, occupational hygienists, and decision makers. Objectives: The objectives of this paper are to compile and summarize the scientific knowledge on occupational exposure to FRs as well as to identify research gaps and to formulate recommendations. Methods: Five databases were consulted for this systematic...
La lambda-cyhalothrine comme insecticide en milieu agricole
Étude de la toxicocinétique de biomarqueurs pour le suivi de l'exposition des travailleurs L'objectif général du présent projet de recherche a été de combler le manque de connaissance sur la toxicocinétique de biomarqueurs d'exposition à la lambda-cyhalothrine chez l'humain, pour une meilleure interprétation des données de biosurveillance des travailleurs exposés à ce pesticide et une meilleure évaluation des risques associés. Ce projet a été divisé en deux...
Current state of knowledge on the health effects of engineered nanomaterials in workers
A systematic review of human studies and epidemiological investigations Objectives: The widespread application of nano-enabled products and the increasing likelihood for workplace exposures make understanding engineered nanomaterial (ENM) effects in exposed workers a public and occupational health priority. The aim of this study was to report on the current state of knowledge on possible adverse effects induced by ENM in humans to determine the toxicological profile of each type of ENM and potential biomarkers for early detection of such effects in workers. Methods: A systematic review of human...
SysDEA: Systematic analysis of dermal exposure to hazardous chemical agents at the workplace
The overall objective of the SysDEA study is to generate scientific knowledge for improvement and standardization of measurement methods for dermal exposure to chemicals at the workplace. To this end, five different tasks (transfer, spreading, spraying, handling immersed objects, and handling contaminated objects) were performed with three different product types: a dusty powder (solids) and high viscosity (HV) and low viscosity (LV) liquids. The investigated exposure situations (product-task combinations) were: dumping powder, pouring LV and HV (transfer), rolling LV and HV (spreading), surface...
Survey of guidelines and current practices for safe handling of antineoplastic and other hazardous drugs used in 24 countries
Purpose A survey of guidelines and current practices was conducted to examine the safe handling procedures for antineoplastic and other hazardous drugs that are used in 24 countries including the Americas, Europe, the Mideast, Far East, and Australia. Methods Subject experts were asked to complete a brief survey regarding safe handling guidelines and practices for hazardous drugs in their countries. Questions addressed practices for handling monoclonal antibodies, the use of closed-system transfer devices, medical surveillance practices, and measurements of compliance with existing guidelines....
Étude comparative des banques de données de mesures d’exposition IMIS (OSHA) et LIMS (IRSST)
Une bonne connaissance des niveaux d'exposition des travailleurs aux contaminants chimiques est fondamentale dans un programme de maîtrise, de prévention et de gestion des risques associés à ces substances. Au Québec, l'Institut de recherche Robert-Sauvé en santé et en sécurité du travail (IRSST) administre un système de gestion de l'information du laboratoire (LIMS – Laboratory Information Management System). Cette banque de données électronique contient l'ensemble des résultats d'analyse...
Historical changes in chemical exposures encountered by Danish firefighters
Objective: This study aimed to demonstrate the possibility of using history science methods in occupational studies by evaluating overall historical changes in Danish firefighting modifying chemical exposures from smoke and fire trucks. Methods: Data on changes in Danish firefighting after World War II were searched for in both museums and the Danish library catalogue REX, accessing collections of literature from all institutes of the University of Copenhagen and the Danish Royal Library. Results: Several historical changes were identified either increasing or reducing chemical exposures in Danish...
Assessment of nanofibre dustiness by means of vibro-fluidization
Dustiness testing probes for the propensity of a powdery material to release dust particles following agitation. For high aspect-ratio materials like nanotubes, the most important dust fraction is that of potentially carcinogenic fibres(WHO-fibres).Wedeveloped the fluidizer particularly for fibres thatmakes use of vibro-fluidization in order to effectively disentangle single fibres and agglomerates of multi-walled carbon nanotube powders. Counting rules for morphological characterization of collected particles by means of electron microscopywere established, allowing quantifying the WHO-fibre fraction...
NF X43-215 - Prélèvement et analyse des aérosols semi-volatils
Exigences et méthodes d'essai Le présent document décrit les procédures de mise au point, de validation et de mise en oeuvre de méthodes de prélèvement et d'analyse d'agents chimiques présents sous la forme d'un mélange de particules aériennes et de vapeur pour l'évaluation des expositions professionnelles. Source: https://www.boutique.afnor.org/norme/nf-x43-215/qualite-de-l-air-air-des-lieux-de-travail-prelevement-et-analyse-des-aerosols-semi-volatils-exigences-et-methodes-d-essai/article/909349/fa191295
Validation of a measurement method for diacetyl using sorbent tubes and thermal desorption
Diacetyl, also known as 2,3-butanedione, and the closely related chemical 2,3-pentanedione, are naturally occurring substances with a characteristic butter-like odour found in foods such as dairy products, beer and fruits. Diacetyl is also added to various food products as artificial butter flavouring and both substances are present in emissions generated by coffee roasting and grinding. Occupational levels of diacetyl exposure has been linked with the lung disease bronchiolitis obliterans which is life threatening and irreversible. In Great Britain, occupational exposure limits to protect workers'...
ASTM E2563 - 18 - Standard Practice for Enumeration of Non-Tuberculosis Mycobacteria in Aqueous Metalworking Fluids by Plate Count Method
This practice allows for the recovery and enumeration of viable and culturable, non-tuberculosis, rapidly growing Mycobacteria ( M. immunogenum , M. chelonae , M. absessus , M. fortuitum , and M. smegmatis ) in the presence of high Gram-negative background populations in metalworking fluid field samples. During the past decade, it has become increasingly apparent that non-tuberculous Mycobacteria are common members of the indigenous MWF bacterial population. This population is predominantly comprised of Gram-negative bacteria and fungi. Mycobacterial contamination of metalworking fluids has been...
ASTM E2564 - 18 - Standard Practice for Enumeration of Mycobacteria in Metalworking Fluids by Direct Microscopic Counting (DMC) Method
During the past decade, it has become increasingly apparent that non-tuberculous mycobacteria are common members of the indigenous MWF bacterial population. Measurement of mycobacterial cell count densities is an important step in establishing a possible relationship between mycobacteria and occupational health-related allergic responses, for example, hypersensitivity pneumonitis (HP) in persons exposed to aerosols of metalworking fluids. It is known that the viable mycobacteria count underestimates the total mycobacterial levels by not counting the non-culturable, possibly dead or moribund population...
Cancer de la vessie et expositions professionnelles aux fluides de coupe
Étude épidémiologique parmi les travailleurs de la sidérurgie en France L'objectif de cette étude est de rechercher s'il existe un risque de cancer de la vessie associé à des expositions professionnelles à des brouillards d'huiles, issus de l'utilisation d'huiles entières ou de fluides aqueux. Une étude cas-témoins a été mise en place au sein d'une cohorte de 22 795 travailleurs de la sidérurgie du Nord - Pas-de-Calais. Les cas de cancer de vessie ont été diagnostiqués...
Development of a bar code-based exposure assessment method to evaluate occupational exposure to disinfectants and cleaning products
A pilot study Objective: Healthcare workers are highly exposed to various types of disinfectants and cleaning products. Assessment of exposure to these products remains a challenge. We aimed to investigate the feasibility of a method, based on a smartphone application and bar codes, to improve occupational exposure assessment among hospital/cleaning workers in epidemiological studies. Methods: A database of disinfectants and cleaning products used in French hospitals, including their names, bar codes and composition, was developed using several sources: ProdHyBase (a database of disinfectants managed...
Surveillance biologique de l’exposition professionnelle (SBEP) aux médicaments anticancéreux au sein d’un hôpital Mauritanien
Contexte: En Mauritanie, l'activité du Centre National d'Oncologie (CNO) n'a cessé de croître, entraînant une augmentation de la manipulation de médicaments anticancéreux (MAC). Dans ce contexte, la contamination des professionnels aux MAC a été évaluée. Méthodes: L'intervention s'est déroulée en 2015, dans 2 services de soins, et a évalué des infirmiers (IDE) préparant et administrant des MAC et des agents en charge de l'hygiène (AH). Chaque participant a...
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