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Programme national de surveillance du mésothéliome pleural (PNSM)
Vingt années de surveillance (1998-2017) des cas de mésothéliome, de leurs expositions et des processus d'indemnisation En 1998, la Direction générale du travail (DGT) et la Direction générale de la santé (DGS) des ministères respectifs ont saisi Santé publique France pour mettre en place un programme national de surveillance des effets sanitaires de l'amiante : le programme national de surveillance du mésothéliome pleural (PNSM), marqueur spécifique des expositions passées à l'amiante...
Sinistralité et repérage des cancers professionnels dans neuf pays européens
EUROGIP publie un nouveau rapport dont les données portent sur l'Allemagne, l'Autriche, la Belgique, le Danemark, la Finlande, la France, l'Italie, la Suède, la Suisse. Les cas (déclarations et reconnaissances) de cancers depuis 2005 sont relativement stables au Danemark, en Belgique, France, Italie et Suède, mais en augmentation en Autriche, Allemagne et Suisse. Pour cette dernière catégorie, les raisons sont diverses, comme l'inscription du cancer de la peau en Allemagne en 2015 sur la liste nationale des MP. Dans tous les pays à...
Cas incidents des maladies à déclaration obligatoire reliées à une exposition professionnelle à l’amiante dans le Système MADO-Chimique, Québec, 2006 – 2015
L'analyse des 2 234 cas incidents de maladies à déclaration obligatoire (MADO) reliées à une exposition professionnelle à l'amiante enregistrés dans le système MADO-Chimique entre 2006 et 2015 montre que : 98 % des cas sont des hommes. Chez les femmes, les mésothéliomes sont les maladies reliées à l'exposition à l'amiante les plus fréquentes, alors que chez les hommes ce sont les amiantoses qui prédominent. Près de 60 % des cas d'amiantose, près de 50 % des cas de...
Mesothelioma incidence and asbestos exposure in Italian national priority
Objectives This study aimed to (i) describe mesothelioma incidence in the Italian national priority contaminated sites (NPCS) on the basis of data available from the Italian National Mesothelioma Registry (ReNaM) and (ii) profile NPCS using Bayesian rank analysis. Methods: Incident cases of mesothelioma and standardized incidence ratios (SIR) were estimated for both genders in each of the 39 selected NPCS in the period 2000–2011. Age-standardized rates of Italian geographical macro areas were used to estimate expected cases. Rankings of areas were produced by a hierarchical Bayesian model...
Faisabilité d’accroître la déclaration obligatoire des maladies liées à une exposition à l’amiante par les médecins des hôpitaux
L'amiantose et le mésothéliome sont des maladies à déclaration obligatoire (MADO) par les médecins du Québec. Or, une faible proportion d'entre eux s'acquitte de cette obligation. Si tous les médecins déclaraient leurs cas, la base de données dans laquelle on enregistre l'information sur les personnes atteintes de MADO, le système MADO-Chimique, serait plus complète et pourrait servir à des fins de surveillance des maladies reliées à l'amiante. Un projet pilote a été...
Incidence of malignant mesothelioma of the pleura in Québec and Canada from 1984 to 2007, and projections from 2008 to 2032
Background: Continuous increase in male incidence of malignant mesothelioma of the pleura (MMP) despite the drop of asbestos production since 1980 in Québec motivated this study aiming to assess when the rates of MMP will decline. Methods: Age-standardized rates and trends were estimated over the 1984–2007 period by sex for Québec versus “Canada-excluding-Québec” (Can-Qc). An age-cohort regression was used to make projections for 2008–2032. Results: Average rates of MMP in Québec men and women were significantly higher than in Can-Qc. Projected...
Mesothelioma in Australia
Incidence (1982 to 2013) and Mortality (1997 to 2012) Mesothelioma is a fatal cancer that typically occurs 20 to 40 years after exposure to asbestos, although exposure does not always result in the disease. Mesothelioma of the pleura (a cancer affecting the protective lining of the lungs and chest cavity) is the most common form of mesothelioma in Australia and has accounted for approximately 93% of cases since 1982. Mesothelioma of the peritoneum (a cancer affecting the abdominal lining) is less common and has accounted for approximately 6% of cases since 1982. The figures in this report include...
The Risk of Lung Cancer After Cessation of Asbestos Exposure in Construction Workers Using Pleural Malignant Mesothelioma as a Marker of Exposure
Objective: To study the risk of lung cancer in heavily asbestos-exposed workers after the exposure to asbestos has ended. Methods: Lung cancer was studied in a cohort of 189,896 Swedish construction workers through a linkage with the Swedish Cancer Registry. Asbestos exposure was estimated by the incidence of malignant mesothelioma in the occupational group. Results: There were in total 2835 cases of lung cancer. Workers with heavy exposure to asbestos had an increased risk of lung cancer (relative risks = 1.74; 95% confidence interval, 1.25 to 2.41) before exposure ended and a similar risk to...
Mesothelioma in Occupational Cohort Studies
Methodological Considerations Objective: This article describes effective strategies for the identification and valid assessment of mortality due to mesothelioma. Methods: We manually reviewed all death certificates for mention of mesothelioma for all International Classification of Diseases (ICD) revisions. We tested the accuracy of our ascertainment method by comparing New Jersey death certificate data from our health status registry with histologically confirmed cases from the New Jersey State Cancer Registry. Results: We found reasonably good agreement between death certificate diagnoses and...
Diseases attributable to asbestos exposure: Years of potential life lost, United States, 1999–2010
Background Although asbestos use has been restricted in recent decades, asbestos-associated deaths continue to occur in the United States. Objectives We evaluated premature mortality and loss of potentially productive years of life attributable to asbestos-associated diseases. Methods Using 1999–2010 National Center for Health Statistics mortality data, we identified decedents aged ≥25 years whose death certificate listed asbestosis and malignant mesothelioma as the underlying cause of death. We computed years of potential life lost to life expectancy (YPLL) and to age 65 (YPLL65). Results...
Short, fine and WHO asbestos fibers in the lungs of Quebec workers with an asbestos-related disease
Background The possible role of short asbestos fibers in the development of asbestos-related diseases and availability of lung fiber burden data prompted this study on the relationships between fiber characteristics and asbestos-related diseases among compensated workers. Methods Data collected between 1988 and 2007 for compensation purposes were used; lung asbestos fibers content of 123 Quebec workers are described according to socio-demographic characteristics, job histories and diseases (asbestosis, mesothelioma, lung cancer). Results Most workers (85%) presented chrysotile fibers in their lungs...
Pneumoconiosis and malignant mesothelioma in a family operated metal casting business that used industrial talc from New York State
Background The United States is second only to the People's Republic of China in annual talc production. U.S. talc is used in the production of ceramics, paint, paper, plastics, roofing, rubber, cosmetics, flooring, caulking, and agricultural applications. A number of U.S. talc deposits consistently contain talc intergrown with amphiboles such as tremolite and/or anthophyllite. It has long been recognized that miners and millers of talc deposits are at risk for pneumoconiosis and it has recently been reported that it is prudent, on the balance of probabilities, to conclude that dusts from New...
Mesothelioma Associated With Commercial Use of Vermiculite Containing Libby Amphibole
Objectives : To describe asbestos-related mortality among manufacturing workers who expanded and processed Libby vermiculite that contained amphibole fiber. Methods : Standardized mortality ratio was calculated for 465 white male workers 31 years after last Libby vermiculite exposure. Results : Two workers died from mesothelioma, resulting in a significantly increased standardized mortality ratio of 10.5 (95% confidence interval, 1.3 to 38.0). These workers were in the upper 10th percentile of cumulative fiber exposure, that is, 43.80 and 47.23 fiber-years/cm3, respectively. One additional worker...
Le mésothéliome : 31e maladie à déclaration obligatoire
« Tout nouveau cas de mésothéliome, quel que soit son site anatomique (plèvre, péritoine, péricarde…), doit désormais être notifié au médecin de l'Agence Régionale de Santé (ARS), par tout médecin (pathologiste ou clinicien) exerçant en France métropolitaine ou ultramarine et qui en pose le diagnostic ». Tel est le contenu du décret nº 2012-47 du 16 janvier 2012 qui ajoute les mésothéliomes à la liste officielle des maladies à déclaration...
Erionite: An Emerging North American Hazard
Erionite is a naturally occurring mineral that belongs to a group of silicate minerals called zeolites. It is usually found in volcanic ash that has been altered by weathering and ground water. Like naturally occurring asbestos, deposits are present in many Western states (see map). Erionite can occur in a fibrous form. Disturbance of this material can generate airborne fibers with physical properties and health effects similar to asbestos. For example, it has long been known that residents of some Turkish villages where erionite-containing rock was used to construct homes have a remarkably high...
Mesothelioma mortality in Great Britain: The revised risk and two-stage clonal expansion models
Asbestos is a known carcinogen that is the cause of the majority of mesothelioma cases worldwide. Various models have been used to describe the increase and likely future pattern of mesothelioma rates seen in many western countries - a legacy of past heavy industrial asbestos use. Following on from previous work (Tan and Warren, 2009), we analysed female mesothelioma mortality using the same risk model that was assumed for males. We also analysed mesothelioma mortality in males in Great Britain using two alternative risk models; the first is based on asbestos import data where the population is...
Mesothelioma in Australia
Incidence 1982 to 2006, mortality 1997 to 2007 Data on the number of new cases of mesothelioma are collected nationally by the Australian Institute of Health and Welfare (AIHW) in the National Cancer Statistics Clearing House, via the State Cancer Registries. Information on deaths from mesothelioma is also collected by the AIHW as part of the National Mortality Database. Data are available from 1982 to 2006 for the number of new cases, and from 1997 to 2007 for the number of deaths. Source : http://www.safeworkaustralia.gov.au/NR/rdonlyres/1CFBDAB6-424E-4936-B351-6EBAE8420BB9/0/MesotheliomaInAustralia2010...
Projection of mesothelioma mortality in Great Britain
There has been an increase in mesothelioma mortality in Great Britain, with 1705 deaths recorded in 2006. In 2005, a statistical model was developed based on a simple birth-cohort model, which assumes that the risk of mesothelioma depends on age and years of exposure and that an individual's asbestos exposure depends on the year of exposure. An optimisation technique was used to fit the model and a profile of the population exposure was estimated. Projections of the future burden of mesothelioma mortality were calculated, however statistical uncertainties in the formulation of the model could...

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