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Occupational exposure to benzene, toluene, xylene and styrene and risk of prostate cancer in a population-based study
Objectives: While several monocyclic aromatic hydrocarbons are classified as definite or possible carcinogens to humans, little data exist on their role in prostate cancer (PCa). We examined occupational exposure to benzene, toluene, xylene (BTX) and styrene and PCa risk in a population-based case–control study in Montreal, Canada. Methods: Cases aged ≤75 years diagnosed with PCa in 2005–2009 (n=1920) and population controls frequency-matched on age (n=1989) provided detailed work histories. Experts evaluated the certainty, frequency and concentration of exposure to monocyclic aromatic...
Cartographie des expositions aux hydrocarbures aromatiques polycycliques (HAP) par secteur d'activité
Focus sur la surveillance biologique des expositions professionnelles L'analyse des données de surveillance biologique des expositions professionnelles (SBEP) aux hydrocarbures aromatiques polycycliques (HAP) publiées au cours de la dernière décennie permet de dresser une cartographie des expositions par secteur d'activité. La stratégie de SBEP, notamment le choix du ou des biomarqueurs pertinents, est discutée pour certains secteurs d'activité pouvant exposer à des HAP dont certains cancérogènes comme la cokerie...
Assessment of Ambient Exposures Firefighters Encounter While at the Fire Station
An Exploratory Study Objective: Firefighters are at an increased risk for many types of cancer. Although most studies on this topic focus on exposures encountered while fighting fires, exposures at the fire station are also cause for concern. This pilot study aimed to describe air quality within a few fire stations in and around Boston, Massachusetts, and to investigate physical and organizational factors that may influence levels of contaminants in stations. Methods: Air sampling of particulate matter less than 2.5 μm in diameter (PM2.5) and particle-bound polycyclic aromatic hydrocarbons ...
Elevated Exposures to Polycyclic Aromatic Hydrocarbons and Other Organic Mutagens in Ottawa Firefighters Participating in Emergency
On-Shift Fire Suppression Occupational exposures to combustion emissions were examined in Ottawa Fire Service (OFS) firefighters. Paired urine and dermal wipe samples (i.e., pre- and post-event) as well as personal air samples and fire event questionnaires were collected from 27 male OFS firefighters. A total of 18 OFS office workers were used as additional controls. Exposures to polycyclic aromatic hydrocarbons (PAHs) and other organic mutagens were assessed by quantification of urinary PAH metabolite levels, levels of PAHs in dermal wipes and personal air samples, and urinary mutagenicity using...
Mise en oeuvre manuelle des polyesters stratifiés
Cette brochure est conçue comme un guide et un document de référence pour la conception, la réception, la conduite et le contrôle des installations de ventilation dans un atelier de polyesters stratifiés. Dans ce guide pratique de ventilation, sont abordés les points suivants : - Généralités sur les matières premières, le niveau de risque, le polluant principal (styrène), le moulage au contact. - Méthodologie d'étude du système de ventilation. - Conception du système de ventilation...
Australian Work Exposures Study (AWES) - Polycyclic aromatic hydrocarbons (PAHs)
The Australian Work Health and Safety Strategy 2012-2022 (the Strategy) describes work-related cancer as a priority disorder and understanding current hazardous exposures and the effectiveness of controls as a research priority. The Australian Work Exposures Study (AWES) was a national survey that investigated work-related exposures among Australian workers to 38 agents classified by the International Agency for Research on Cancer (IARC) as known or suspected carcinogens. Some polycyclic aromatic hydrocarbons (PAHs) are classified as a known or suspected human carcinogens by the IARC and the work...
Maternal occupational exposure to polycyclic aromatic hydrocarbons and small for gestational age offspring
Objectives: While some of the highest maternal exposures to polycyclic aromatic hydrocarbons (PAHs) occur in the workplace, there is only one previous study of occupational PAH exposure and adverse pregnancy outcomes. We sought to extend this literature using interview data combined with detailed exposure assessment. Methods: Data for 1997–2002 were analysed from mothers of infants without major birth defects in the National Birth Defects Prevention Study, a large population-based case-control study in the USA. Maternal telephone interviews yielded information on jobs held in the month before...
Occupational exposure to solvents and acute myeloid leukemia
A population-based, case–control study in four Nordic countries Objective: The aim of the current study was to assess the relation between occupational exposure to solvents and the risk of acute myeloid leukemia (AML). Methods: Altogether, this study comprises 15 332 incident cases of AML diagnosed in Finland, Norway, Sweden and Iceland from 1961–2005 and 76 660 controls matched by year of birth, sex, and country. Occupational records were linked with Nordic Occupational Cancer Study job exposure matrix (JEM) to estimate quantitative values for 26 occupational exposure factors. Hazard...
Urinary S-phenylmercapturic Acid as a Key Biomarker for Measuring Occupational Exposure to Low Concentrations of Benzene in Chinese Workers
A Pilot Study Objective: This study analyzed the level of urinary S-phenylmercapturic acid (U-SPMA) for low benzene exposure in a group of Chinese shoe-making workers. Methods: Urinary samples from 55 workers exposed to benzene at levels lower than 10 parts per million (ppm) were collected at postshift. U-SPMA level was determined using high-performance liquid chromatography/mass spectrography (HPLC/MS) method. Results: Good linearity of U-SPMA was observed within the range from 10 to 320 μg/L (r = 0.9994). Concentration of airborne benzene ranged from 0.71 to 32.17 mg/m3, and three segments...
Bitumes : l´Agence française de sécurité sanitaire de l´environnement et du travail évalue les risques pour la santé des travailleurs
L´agence française de sécurité sanitaire de l´environnement et du travail (Afsset) a été saisie par la Confédération générale du travail (CGT) dans le but de réaliser une évaluation des risques pour la santé des travailleurs liés à l’usage des bitumes. La saisine de l´Afsset ne porte pas sur le cas d´EUROVIA, mais a une portée générale. Source: http://www.afsset.fr/index.php?pageid=452&newsid=566&MDLCODE=news
NIOSH and USFA Initiate Study of Cancer among Firefighters
The National Institute for Occupational Safety and Health (NIOSH) and the United States Fire Administration (USFA) are partnering on a study to examine the potential for increased risk of cancer among firefighters due to exposures from smoke, soot, and other contaminants in the line of duty. This multi-year USFA supported NIOSH study will include over 18,000 current and retired career firefighters. The project will improve upon previously published firefighter studies by significantly increasing the number of individuals for whom health data will be analyzed. A larger study provides greater statistical...
Effets des pics de concentration sur la neurotoxicité du styrène dans l’industrie de plastique renforcé de fibre de verre
Le projet de recherche avait deux objectifs principaux. D'une part, nous voulions faire des mesures en continu dans les milieux de travail pour bien connaître les profils d'exposition des travailleurs de l'industrie du plastique renforcé de fibre de verre (IPRFV). D'autre part, nous voulions savoir s'il est possible que de « fortes » expositions pendant de courtes périodes de temps, les « pics », puissent avoir un effet sur le système nerveux des travailleurs. Source : http://www.irsst.qc.ca/files/documents/PubIRSST/R-640.pdf
Évaluation des risques sanitaires associés à l’inhalation de composés organiques volatiles, métaux lourds et hydrocarbures aromatiques polycycliques autour de 3 zones multi-émettrices en Rhône-Alpes
Certaines zones en Rhône-Alpes concentrent à la fois de nombreuses industries, un important trafic routier et de grandes populations, ce qui pose la question de l’impact sanitaire des émissions atmosphériques sur ces zones. Trois zones ont été retenues pour l’étude, où l’industrie chimique est particulièrement implantée : le sud lyonnais (Pierre-Bénite, Saint-Fons), le sud grenoblois (Pont-de-Claix, Jarrie) et la moyenne vallée du Rhône (Roussillon, Salaise-sur-Sanne). Dans un but d’information...

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