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Urinary S-phenylmercapturic Acid as a Key Biomarker for Measuring Occupational Exposure to Low Concentrations of Benzene in Chinese Workers
A Pilot Study Objective: This study analyzed the level of urinary S-phenylmercapturic acid (U-SPMA) for low benzene exposure in a group of Chinese shoe-making workers. Methods: Urinary samples from 55 workers exposed to benzene at levels lower than 10 parts per million (ppm) were collected at postshift. U-SPMA level was determined using high-performance liquid chromatography/mass spectrography (HPLC/MS) method. Results: Good linearity of U-SPMA was observed within the range from 10 to 320 μg/L (r = 0.9994). Concentration of airborne benzene ranged from 0.71 to 32.17 mg/m3, and three segments...

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