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IARC Scientific Publication No. 165: Tumour Site Concordance and Mechanisms of Carcinogenesis
The International Agency for Research on Cancer (IARC) has published a new Scientific Publication that reviews the information on cancer sites and mechanistic events for the more than 100 agents classified in Group 1 (carcinogenic to humans) by the IARC Monographs Programme. This publication is based on a systematic identification and comparison of the cancer sites observed in humans and those observed in experimental animals, as well as a compilation of mechanistic events for agents known to cause cancer in humans. Relevant information was analysed on all the agents classified in Group 1 in IARC...
Agents fibrogènes et cancérogènes dans les mines d’or et de fer du Québec - Étude exploratoire
De récentes études ont mis en évidence que les travailleurs des mines d’or du Dakota et des mines de fer du Minnesota sont exposés à des particules minérales allongées (PMA). En particulier, les mineurs du Minnesota présentent un risque plus élevé de décès par cancer du poumon, par mésothéliome et par maladies cardiaques que la population générale. Comme l’intérêt renouvelé pour l’exploration de nouveaux gisements d’or et de fer dans le Nord...
Welding, Molybdenum Trioxide, and Indium Tin Oxide
IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Volume 118 This volume of the IARC Monographs provides evaluations of the carcinogenicity of welding and welding fumes, molybdenum trioxide, and indium tin oxide. Worldwide, an estimated 11 million workers have a job title of welder, and around 110 million additional workers probably incur welding-related exposures. Welding can involve exposures to fumes, gases, ultraviolet radiation and electromagnetic fields, and co-exposures to asbestos and solvents. The extent and type of exposure can depend on the process used, the material...
Exposition des salariés à de multiples nuisances cancérogènes en 2010
Introduction – Les facteurs professionnels susceptibles d'augmenter les risques de cancer sont généralement étudiés séparément les uns des autres, alors que les expositions aux agents cancérogènes sont souvent multiples. L'objectif de ce travail était de fournir des indicateurs d'exposition des salariés à un ensemble de cancérogènes, chimiques ou non, et d'identifier des groupes de salariés particulièrement exposés à des fins de prévention. Méthode...
Surveillance médico-professionnelle des travailleurs exposés ou ayant été exposés à des agents cancérogènes pulmonaires
Ces recommandations de bonnes pratiques ont pour objectif de définir la surveillance médicoprofessionnelle des travailleurs exposés ou ayant été exposés à des agents cancérogènes pulmonaires, en répondant notamment aux interrogations des professionnels de santé et des travailleurs sur l'opportunité de les faire bénéficier d'un dépistage du cancer broncho-pulmonaire. Élaborées à la demande de la Direction générale du travail par la Société...
Carcinogens that should be subject to binding limits on workers’ exposure
The objective of this publication is the identification of at least 70 carcinogens that are relevant for workers’ exposure via inhalation at a considerable number of workplaces in Europe and thus, for which a Binding Occupational Exposure Limits (BOEL) under the Carcinogens and Mutagens Directive (CMD) might be suggested. Source: http://www.etui.org/Publications2/Reports/Carcinogens-that-should-be-subject-to-binding-limits-on-workers-exposure
Carcinogenicity of some industrial chemicals
In February 2016, 24 experts from eight countries met at the International Agency for Research on Cancer (IARC), Lyon, France, to assess the carcinogenicity of seven industrial chemicals (appendix). These assessments will be published as volume 115 of the IARC Monographs. Source: Yann Grosse, Dana Loomis, Kathryn Z Guyton, Fatiha El Ghissassi, Véronique Bouvard, Lamia Benbrahim-Tallaa, Heidi Mattock, Kurt Straif. The Lancet Oncology , 2016. http://dx.doi.org/10.1016/S1470-2045(16)00137-6
Les expositions aux cancérogènes, mutagènes et reprotoxiques
Un zoom sur huit produits chimiques Les améliorations sont cependant hétérogènes. L'analyse des huit agents CMR qui touchent le plus de salariés montre que l'exposition au formaldéhyde, au plomb, à l'amiante et aux poussières de bois a fortement diminué tandis que celles à d'autres produits comme la silice cristalline ou les phtalates, important reprotoxique, a plutôt augmenté. Les mesures de protections efficaces contre les produits comme les gaz d'échappement diesel ou les huiles minérales...
Exposure to carcinogens and work-related cancer
A review of assessment methods Estimates of the recent and future burden of occupational diseases indicate that occupational cancer is still a major problem and will remain so in the future as a result of exposure of workers to carcinogens. That's why occupational cancer is a problem that needs to be tackled across the European Union. This summary provides a short overview of assessment tools for the exposure to cancer risk factors and looks into relevant occupational factors: chemical, physical and biological exposures, as well as other possibly carcinogenic working environment conditions...
Exposure to carcinogens and work-related cancer
A review of assessment methods Occupational cancer is a problem that needs to be tackled across the European Union (EU). Estimates of the recent and future burden of occupational diseases indicate that occupational cancer is still a problem and will remain so in the future as a result of exposure of workers to carcinogens. The goals to which this review aims to contribute are to: - describe occupational exposure to carcinogens and cancer-causing or -promoting working conditions at European, national and workplace levels; - evaluate existing sources of information, identify major knowledge gaps...
Australian Work Exposures Study (AWES) - Polycyclic aromatic hydrocarbons (PAHs)
The Australian Work Health and Safety Strategy 2012-2022 (the Strategy) describes work-related cancer as a priority disorder and understanding current hazardous exposures and the effectiveness of controls as a research priority. The Australian Work Exposures Study (AWES) was a national survey that investigated work-related exposures among Australian workers to 38 agents classified by the International Agency for Research on Cancer (IARC) as known or suspected carcinogens. Some polycyclic aromatic hydrocarbons (PAHs) are classified as a known or suspected human carcinogens by the IARC and the work...
Australian Work Exposures Study (AWES) - Formaldehyde
The Australian Work Health and Safety Strategy 2012-2022 (the Strategy) describes work-related cancer as a priority disorder and understanding current hazardous exposures and the effectiveness of controls as a research priority. The Australian Work Exposures Study (AWES) was a national survey that investigated work-related exposures among Australian workers to 38 agents classified by the International Agency for Research on Cancer (IARC) as known or suspected carcinogens. Formaldehyde is classified as a known human carcinogen by the IARC and the work described in this report uses AWES data to:...
Australian Work Exposures Study (AWES) - Lead and lead compounds
The Australian Work Health and Safety Strategy 2012-2022 (the Strategy) describes work-related cancer as a priority disorder and understanding current hazardous exposures and the effectiveness of controls as a research priority. The Australian Work Exposures Study (AWES) was a national survey that investigated work-related exposures among Australian workers to 38 agents classified by the International Agency for Research on Cancer (IARC) as known or suspected carcinogens. Some forms of lead are considered to be probable carcinogens and the work described in this report uses AWES data to: •...
Opportunities for cancer prevention: trends in the use and release of carcinogens in Massachusetts
The report draws on 20 years of data collected from industries reporting to the Massachusetts Toxic Use Reduction Act program to assess trends in the use and release of chemicals associated with cancer. The analysis shows that reported use and releases of carcinogens among Massachusetts companies have decreased dramatically over time. Reported use declined 32% from 1990 to 2010, and reported releases declined 93% from 1991 to 2010. The report also groups the chemicals by their links with eleven specific types of cancer: bladder; brain and central nervous system; breast; kidney; leukemia; liver;...
Substances cancérogènes
Portrait de l’exposition des travailleurs québécois La liste des substances et conditions de travail associées à un risque élevé de cancer en milieu de travail ne cesse d’augmenter et la CSST a placé les substances cancérogènes parmi les priorités de son plan de mise en œuvre 2008-2010. L’IRSST travaille depuis des années sur certains cancérogènes avérés (selon le Centre international de recherche sur le cancer), tels que le béryllium et la silice. Cependant, afin...
US adds formaldehyde to list of carcinogens
As reported by Reuters, the U.S. government has added formaldehyde, a substance found in plastics and other commonly used products, to a list of known carcinogens and warned that the chemical styrene might cause cancer. In a report prepared for the Secretary of the Department of Health and Human Services (HHS), scientists warned that people with higher exposure to formaldehyde were more at risk for nasopharyngeal cancer, myeloid leukaemia and other cancers. Source : http://www.hazmatmag.com/news/us-adds-formaldehyde-to-list-of-carcinogens/1000473080/
Work exposure to diesel fumes tied to lung cancer
The study has a number of key limitations, one being a lack of data on the subjects' actual exposure to diesel exhaust. Moreover, case-control studies can offer only limited evidence of an association between two variables (in this case, diesel-exhaust exposure and lung cancer risk). And they cannot establish the extent to which diesel exhaust might affect any one worker's absolute risk of developing lung cancer. Studies that follow a population of initially healthy people over time offer stronger evidence of whether a particular exposure is related to a disease risk. Straif noted that...
Identification of research needs to resolve the carcinogenicity of high-priority IARC carcinogens
The purpose was two-fold: (1) identify research needs to address the information needs and gaps for a more definitive classification, and (2) Create a report that will be of value to funding agencies in determining possible projects to support. For each agent, a common reporting template was used. All templates had the following categories : • Summary • Citation for most recent IARC review • Current evaluation • Exposure and biomonitoring • Cancer in humans • Cancer in experimental animals bull; Mechanisms of carcinogenicity • Research needs and recommendations...
Dangerous chemicals putting workers' lives at risk says TUC
Employers who risk the future health of their employees by exposing them to cancer-causing chemicals at work should be prosecuted under UK safety laws, says the TUC today (Thursday) as it produces a new guide for unions. Launching a campaign to raise awareness of the toxic chemicals and substances such as wood dust and diesel particles that can make workers ill sometimes years after leaving their jobs, the TUC guide aims to help union safety reps keep up the pressure on employers to make workplaces safer, and stop them from taking unnecessary risks with their employees' lives. http://www.tuc...
American Experts Say Cancer Prevention Efforts Currently Lacking
The United States federal government has done surprisingly little to assess and reduce workplace exposures to carcinogens, according to a former chief regulatory official with the American Occupational Safety and Health Administration (OSHA). http://www.whsc.on.ca/whatnews2.cfm?autoid=489

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