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Risques pour l’audition d’une exposition combinée bruit et solvants
Résultats d'étude INRS sur le disulfure de carbone et les bruits impulsionnels. Une étude de l'INRS montre que l'exposition au disulfure de carbone, solvant a priori sans effet ototoxique, et aux bruits impulsionnels (non continus) peut entraîner un risque accru de pertes auditives, ce même en dessous de la valeur limite d'exposition au bruit. D'autres effets réversibles peuvent aussi être observés, comme une augmentation de la fatigue auditive en présence de bruit continu. Ces mécanismes non identifiés...
Ototoxic chemicals
Chemicals that result in hearing loss It is well documented that occupational noise exposure is a significant health hazard that leads to permanent noise-induced hearing loss (NIHL) and we have the National Exposure Standard for Occupational Noise to deal with this. It is less well known that a substantial number of medications and common industrial chemicals can also cause hearing loss themselves or exacerbate the effects of noise. These chemicals are said to be ototoxic (oto = ear, toxic = poisonous). They may damage the cochlea in the inner ear and/or the auditory neurological pathways leading...
Bruit et substances ototoxiques : cocktail à risque pour l’audition
De nombreuses études ont mis en évidence un risque accru de troubles auditifs du fait de phénomènes de synergies entre certains agents chimiques et le bruit. Quelles sont les substances concernées ? Comment fonctionnent ces co-expositions? Quels sont les effets sur l'homme ? Cet article apporte un éclairage sur ces questions. Source: http://www.hst.fr/inrs-pub/inrs01.nsf/IntranetObject-accesParReference/HST_DC%208/$File/DC8.pdf
The co-exposure to noise and a mixture of solvents has an additive effect in the prevalence of hypertension
The aim of this study was to investigate interaction of noise and mixed organic solvents on blood pressure. Biological interaction of two variables on hypertension was calculated using the synergistic index. The results indicate that exposure to noise or a mixture of organic solvents may be associated with the prevalence of hypertension in car manufacturing company workers and co-exposure to noise and a mixture of solvents has an additive effect in this regard. Therefore appropriate preventive programs in these workers recommended. Source : Mirsaeed Attarchi et al. Combined effects of exposure...
Conférence INRS 2012 sur la recherche en santé au travail : Risques pour la santé liés aux multiexpositions
Cette conférence sera la deuxième d’une série de conférences organisées par l’INRS sur la recherche en matière de Santé et de Sécurité au travail. Elle abordera essentiellement les effets inhérents aux multiexpositions. Elle a pour vocation de rassembler chercheurs, experts et médecins d’horizons différents pour partager les dernières connaissances et discuter des besoins en recherche sur les thèmes suivants: Expositions au bruit et aux agents ototoxiques, Interaction de plusieurs...
Combined exposure to Noise and Ototoxic Substances
Noise-induced hearing loss remains one of the most prominent occupational diseases in Europe. However, noise is no longer perceived as the only source of work-related hearing damage and increasing attention is being paid to the risks of combined exposure to high-level noise and ototoxic substances, that is, those which can affect the structures and/or the function of the inner ear and the associated signal transmission pathways in the nervous system. This publication aims to provide an up-to-date picture of our knowledge in this field. It includes: a description of the basic features of the physiological...
Evaluation of Health Concerns at a Printed Circuit Board Manufacturing Plant
The Health Hazard Evaluation (HHE) Programme evaluated employees' concerns about exposure to lead solder paste and fumes and noise at a printed circuit board manufacturing plant. Investigators found that auto insertion operators' noise exposures were very low. Investigators found lead on employees' hands, on work surfaces, and in a break room. Investigators recommended improving general housekeeping and using engineering controls when removing solder dross and cleaning wave solder machines. Source : http://www.cdc.gov/niosh/hhe/reports/pdfs/2007-0201-3086.pdf
Chemicals and Noise
A Hazardous Combination It is no surprise that most work-related hearing loss is caused by noise exposure, and that genetics and age can also be contributors. What may not be as well known is that some chemical exposures can pose a potential risk to hearing. Both animal experiments and human studies suggest that certain chemical exposures may cause "ototoxic" effects (damage the hearing and balance functions of the ear). In general, the exposure concentrations that cause these effects are considered high. However, exposure to some of these chemicals and noise at the same time can significantly...

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