Parcourir par tags

Tous les tags » Analyse de risques (RSS)
Dioxyde de titane sous forme nanoparticulaire : l’Anses définit une Valeur Toxicologique de Référence (VTR) pour l’exposition chronique par inhalation
Le dioxyde de titane sous forme nanoparticulaire est utilisé dans de nombreuses applications industrielles et commerciales. Dans le cadre de sa mission nationale d'élaboration de valeurs sanitaires de référence, l'Anses a été chargée de définir une Valeur Toxicologique de Référence (VTR) pour le dioxyde de titane sous forme nanoparticulaire (TiO 2 -NP). Suite à une analyse approfondie de l'ensemble des données de toxicité disponibles, l'Agence recommande une VTR chronique par inhalation pour...
New reports on alternatives assessment and substitution of harmful chemicals
A Cross Country Analysis of Approaches to Support Alternatives Assessment and Substitution of Chemicals of Concern that describes and gives a list of approaches developed across countries and by different stakeholders to support alternatives assessment and substitution of chemicals of concern. Source : http://www.oecd.org/fr/securitechimique/substitution-of-hazardous-chemicals.htm
A Review of Workplace Risk Management Measures for Nanomaterials to Mitigate Inhalation and Dermal Exposure
This review describes an evaluation of the effectiveness of Risk Management Measures (RMM) for nanomaterials in the workplace. Our aim was to review the effectiveness of workplace RMM for nanomaterials and to determine whether established effectiveness values of conventional chemical substances applied for modelling purposes should be adopted or revised based on available evidence. A literature review was conducted to collate nano-specific data on workplace RMM. Besides the quantitative efficacy values, the library was populated with important covariables such as the study design, measurement type...
Projet Amiante-Meta: bilan et perspectives
Quel bilan peut-on tirer du projet Amiante-Meta, lancé en 2012, pour accompagner les entreprises dans la mise en place d'actions de prévention des risques liés à l'amiante ? Cet article fait le point sur tous les aspects abordés dans ce projet (métrologie, mutualisation des données, vérification des facteurs de protection, nouveaux matériels) et dessine les perspectives d'actions à mettre en oeuvre pour poursuivre l'amélioration de la gestion du risque amiante. Source: http://www.inrs.fr/media.html?refINRS...
Nanomatériaux : Anticiper et maîtriser les risques
Chimie, agroalimentaire, construction... De nombreux secteurs industriels tirent aujourd'hui parti des potentialités offertes par le développement des nanomatériaux. Mais leur mise en œuvre suscite de nombreuses interrogations en matière de santé au travail. Quels sont les dangers pour les salariés qui fabriquent ou utilisent des nanomatériaux ? Quelles sont les voies d'exposition possibles ? Quelles protections mettre en place pour garantir des conditions de sécurité optimales pour les travailleurs concernés ?...
Are Operating Room Nurses at Higher Risk of Severe Persistent Asthma? The Nurses' Health Study
Objective : To assess the associations between operating room (OR) nursing, a category of health care workers at high risk of exposure to various inhaled agents, and asthma severity/control among women with asthma. Methods : The level of severity/control in nurses with prevalent doctor-diagnosed asthma in 1998/2000 was compared, using nominal logistic regression, in OR nursing (n = 69) and administrative nursing (n = 546) from the US Nurses' Health Study for whom detailed information on asthma and nursing employment status was available. Results : We observed a significant association between...
ChemView – A web-based tool
The U.S. Environmental Protection Agency (EPA) has launched a web-based tool, called ChemView, to significantly improve access to chemical specific regulatory information developed by EPA and data submitted under the Toxic Substances Control Act (TSCA). “This online tool will improve access to chemical health and safety information, increase public dialogue and awareness, and help viewers choose safer ingredients used in everyday products,” said James Jones, assistant administrator for the Office of Chemical Safety and Pollution Prevention. “The tool will make chemical information...
Guidance for manufactured nanomaterials from the Committee
The German Committee on Hazardous Substances (AGS) has issued Announcement 527 “Manufactured Nanomaterials”. The objective of the Announcement is to give recommendations for the protection of the safety and health of workers handling substances, mixtures, or articles consisting of, or containing, manufactured nanomaterials. The basis is the 2012 European Commission recommendation on the definition of the term ‘nanomaterial‘. Natural and incidental nanomaterials are not considered. Likewise, it does not address use by consumers. Though the announcement is indicative and complements...
Nanoparticules : Efficacité des filtres de protection respiratoire
Afin de minimiser l'exposition de travailleurs aux nanoparticules, une équipe de chercheurs a conçu une méthodologie permettant d'évaluer l'efficacité des appareils de protection respiratoire (APR) en reproduisant en laboratoire les conditions d'exposition à des particules de différentes tailles. À l'aide d'un banc d'essai expérimental, équipé d'un dispositif d'épuration d'air, les scientifiques ont analysé le rendement des filtres N95, soit ceux le plus couramment...
WHO Launches Chemical Risk Assessment Network
Chemicals play a vital part in our daily life. Chemicals can also cause unintended harm to human health. More than 25% of the global burden of disease is linked to environmental factors, including chemicals exposures. The production and use of chemicals continues to increase worldwide, particularly in rapidly developing economies. Enhanced global efforts are needed to share expertise, to assess, and to manage the risks associated with exposure to hazardous chemicals. There is a need to identify knowledge gaps and emerging issues, and to provide a forum for scientific exchange and collaboration...
Guidance document on developing and assessing adverse outcome pathways
The Adverse Outcome Pathway (AOP) methodology is an approach which provides a framework to collect, organise and evaluate relevant information on chemical, biological and toxicological effect of chemicals. This approach supports the use of a mode (and/or mechanism) of action basis for understanding adverse effects of chemicals. This guidance document intends to provide an insight into which pieces of information are necessary to identify and document an AOP and how to present them. It also provides initial assistance on how to undertake the assessment of an AOP in terms of its relevance and adequacy...
Les nanomatériaux sur le lieu de travail. Quels enjeux pour la santé des travailleurs ?
"L'ETUI mène depuis plusieurs années un travail d'information sur les nanotechnologies. Une contribution supplémentaire est apportée avec cette brochure qui traite de la production et de l’utilisation de nanomatériaux sur les lieux de travail. La mise sur le marché et la diversification des usages des nanomatériaux se font à un rythme effréné, alors que l’impact sociétal est loin d’avoir été suffisamment débattu et que le cadre réglementaire européen paraît...
Evaluation of Biomonitoring Data from the CDC National Exposure Report in a Risk Assessment Context: Perspectives across Chemicals
Background : Biomonitoring data reported in the National Report on Human Exposure to Environmental Chemicals [NER; Centers for Disease Control and Prevention (2012)] provide information on the presence and concentrations of > 400 chemicals in human blood and urine. Biomonitoring Equivalents (BEs) and other risk assessment–based values now allow interpretation of these biomonitoring data in a public health risk context. Objectives : We compared the measured biomarker concentrations in the NER with BEs and similar risk assessment values to provide an across-chemical risk assessment perspective...
Evaluation of Systemic Health Effects Following Dermal Exposure to Chemicals - TR 119
Risk assessment of chemicals, including the REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) legislation, also cover assessments of dermal risk arising from exposure to chemicals. The European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC) has produced this guidance consisting of a tiered approach for the risk assessment of dermal exposure to a chemical. The process developed by the Task Force consists of three linked decision trees, i.e.: Derivation of a health-based reference value; Initial risk characterisation; Refined risk characterisation. It is...
The Future of Exposure Assessment: Perspectives From the X2012 Conference
The British Occupational Hygiene Society, in collaboration with the Institute of Occupational Medicine, the University of Manchester, the UK Health and Safety Executive, and the University of Aberdeen hosted the 7th International Conference on the Science of Exposure Assessment (X2012) on 2 July–5 July 2012 in Edinburgh, UK. The conference ended with a special session at which invited speakers from government, industry, independent research institutes, and academia were asked to reflect on the conference and discuss what may now constitute the important highlights or drivers of future exposure...
Occupational exposure to lead and lung cancer: results from two case-control studies in Montreal, Canada
Objectives We investigated the association between workplace lead exposure and lung cancer risk, separately for organic lead and for inorganic lead, from either engine emissions or from other sources. Methods Two population-based case-control studies were carried out in Montreal (1979–1986 and 1996–2002) to investigate occupational factors in relation to lung cancer among 1593 men with histologically confirmed incident lung cancer, and 1426 controls from the general population. Interviews elicited information on sociodemographic characteristics, lifetime smoking and occupational history...
Identification of Workers Exposed Concomitantly to Heat Stress and Chemicals
In the context of climate change, concomitant exposure to heat stress and chemicals takes on great importance. However, little information is available in this regard. The purpose of this research, therefore, was to develop an approach aimed at identifying worker groups that would be potentially most at risk. The approach comprises 5 consecutive steps: – Establishment of a list of occupations for all industry sectors – Determination of heat stress parameters – Identification of occupations at risk of heat stress – Determination of exposure to chemicals – Identification...
Document unique et risques biologiques (ED 4410)
Aider les entreprises à mieux intégrer le risque biologique dans leur document unique, c'est l'objectif de cette fiche pratique. Elle décrit notamment les 4 types de risques biologique, les principaux secteurs concernés et les grands principes de la transmission des agents biologiques. Dans cette fiche - fiche-socle de la collection "Fiche agents biologiques" -, il est fait un rappel : - des quatre types de risques biologiques ; - de la variété des secteurs professionnels concernés ; - de la chaîne de transmission : le fil...
TR 116 : Category approaches, read-across, (Q)SAR
An accepted practice for the assessment of human health and environmental safety of chemicals is the use of models and analogues to fill data gaps for specific endpoints either for single or multiple chemicals that share structural similarities, and/or comparable reactivity or similarities in metabolism in mammals, fish and other organisms. For example, this approach is acceptable, with limitations, in preparing dossiers for REACH, and it supports efforts for reducing animal testing. The OECD has published guidance on the formation and use of chemical categories for data gap filling. An ECETOC...
Silver Nanoparticles: NIOSH Seeks Information and Comment
Federal Register carried a notice from the National Institute for Occupational Health and Safety (NIOSH) requesting information and comments regarding silver nanoparticles. NIOSH has initiated an evaluation of the scientific data on silver nanoparticles (AgNPs) to ascertain the potential health risks to workers and to identify gaps in knowledge so that appropriate laboratory and field research studies can be conducted. . . . Source : http://www.nanolawreport.com/2012/12/articles/silver-nanoparticles-niosh-seeks-information-and-comment/#axzz2FWeaNAg8 http://www.nanolawreport.com/uploads/file/77...
Filling the Knowledge Gaps for Safe Nanotechnology in the Workplace
A Progress Report from the NIOSH Nanotechnology Research Center, 2004–2011. This 2012 update presents the program accomplishments of the NTRC from its inception in 2004 through 2011. It includes an analysis of the progress made toward accomplishing the goals and objectives of the NIOSH Strategic Plan for Nanotechnology Research and toward addressing the goals and research needs identified in the U.S. National Nanotechnology Initiative (NNI) Environmental, Health, and Safety (EHS) research strategy. Source : http://osha.europa.eu/en/news/int-filling-the-knowledge-gaps-for-safe-nanotechnology...
A Road Map Toward a Globally Harmonized Approach for Occupational Health Surveillance and Epidemiology in Nanomaterial Workers
Objective: Few epidemiological studies have addressed the health of workers exposed to novel manufactured nanomaterials. The small current workforce will necessitate pooling international cohorts. Method : A road map was defined for a globally harmonized framework for the careful choice of materials, exposure characterization, identification of study populations, definition of health endpoints, evaluation of appropriateness of study designs, data collection and analysis, and interpretation of the results.Results: We propose a road map to reach global consensus on these issues. The proposed strategy...
Nanotechnology-theme in new Barents Newsletter
Research Professor Harri Alenius comments on his Editorial in the latest Barents Newsletter: "Nanotechnologies using Engineered nanomaterials (ENMs) are envisaged to become the cornerstone for a number of industrial sectors, from micro-electronics, materials, paper, textile, to energy and cosmetics, industries which are all capable of incorporating some nano-scale-enabled properties into their goods. However, the well-documented issues regarding the safety of ENM have given rise to increasing concerns not only for regulators and the general public but also for industries. A clear understanding...
Shale gas extraction in the UK: A review of hydraulic fracturing
The health, safety and environmental risks associated with hydraulic fracturing (often termed 'fracking') as a means to extract shale gas can be managed effectively in the UK as long as operational best practices are implemented and enforced through regulation. Source : Source : http://www.raeng.org.uk/news/publications/list/reports/Shale_Gas.pdf
Banding the world together; the global growth of control banding and qualitative occupational risk management
Control Banding (CB) strategies to prevent work-related illness and injury for 2.5 billion workers without access to health and safety professionals has grown exponentially this last decade. CB originates from the pharmaceutical industry to control active pharmaceutical ingredients without a complete toxicological basis and therefore no occupational exposure limits. CB applications have broadened into chemicals in general - including new emerging risks like nanomaterials and recently into ergonomics and injury prevention. CB is an action-oriented qualitative risk assessment strategy offering solutions...
Plus de Messages Page suivante »

Abonnement courriel

Messages récents

Catégories

Mots-Clés (Tags)

Blogoliste

Archives