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Effects of occupational exposure to respirable quartz dust on acute myocardial infarction
Objectives: The aim of this study is to investigate the effects of occupational exposure to respirable quartz (RQ) on first acute myocardial infarction (AMI). RQ causes pulmonary diseases like silicosis and has also been linked to cardiovascular diseases. Inflammation is hypothesised as the underlying pathway. Methods: We performed a 1:3 matched case–control study nested in a cohort of male uranium miners. We included cases (identified from hospital records and validated according to WHO criteria) who had suffered their first AMI while still employed and <65 years of age. Controls were...
Evaluation of high blood pressure and obesity among US coal miners participating in the Enhanced Coal Workers' Health Surveillance Program
Since 2005, the Enhanced Coal Workers' Health Surveillance Program (ECWHSP) has offered respiratory examinations to coal miners in a mobile examination unit. As little is known about the cardiovascular health of coal miners, we describe the prevalence of high blood pressure (BP) and obesity among ECWHSP participants. During 2015, 1402 ECWHSP health examinations were performed. The prevalence of BP consistent with hypertension (systolic BP ≥ 140 mm Hg or diastolic BP ≥ 90 mm Hg), prehypertension (systolic BP 120-139 mm Hg or diastolic BP 80-89 mm Hg), and hypertensive crisis (systolic...
Fire Simulation and Cardiovascular Health in Firefighters
Background: Rates of myocardial infarction in firefighters are increased during fire suppression duties, and are likely to reflect a combination of factors including extreme physical exertion and heat exposure. We assessed the effects of simulated fire suppression on measures of cardiovascular health in healthy firefighters. Methods: In an open-label randomized crossover study, 19 healthy firefighters (age, 41±7 years; 16 males) performed a standardized training exercise in a fire simulation facility or light duties for 20 minutes. After each exposure, ex vivo thrombus formation, fibrinolysis...
The association between blood lead levels and cardiovascular diseases among lead-exposed male workers
The contribution of lead exposure to cardiovascular disease is not yet fully understood. This study found an association between blood lead levels and increased hospital admission of ischemic heart diseases and cerebrovascular diseases. Greater efforts are needed to reduce lead exposure for the prevention of cardiovascular diseases. Source: Min, Y. S., & Ahn, Y. S. (2017). Scandinavian Journal of Work, Environment & Health. . http://dx.doi.org/10.5271/sjweh.3631
Are the Associations of Cardiac Acceleration and Deceleration Capacities With Fine Metal Particulate in Welders Mediated by Inflammation?
Objective: The aim of this study was to investigate whether associations of acceleration capacity (AC) and deceleration capacity (DC) with metal-PM2.5 are mediated by inflammation. Methods: We obtained PM2.5, C-reactive protein, interleukin (IL)-6, 8, and 10, and electrocardiograms to compute AC and DC, from 45 male welders. Mediation analyses were performed using linear mixed models to assess associations between PM2.5 exposure, inflammatory mediator, and AC or DC, controlling for covariates. Results: The proportion of total effect of PM2.5 on AC or DC (indirect effect) mediated through IL-6 on...
Long-Term Metal PM2.5 Exposures Decrease Cardiac Acceleration and Deceleration Capacities in Welders
Objective: The aim of the study was to clarify whether long-term metal particulates affect cardiac acceleration capacity (AC), deceleration capacity (DC), or both. Methods: We calculated chronic exposure index (CEI) for PM2.5 over the work life of 50 boilermakers and obtained their resting AC and DC. Linear regression was used to assess the associations between CEI PM2.5 exposure and each of AC and DC, controlling for age, acute effects of welding exposure, and diurnal variation. Results: Mean (standard deviation) CEI for PM2.5 exposure was 1.6 (2.4)?mg/m3-work years and ranged from 0.001 to 14...
Acute Cardiovascular Effects of Firefighting and Active Cooling During Rehabilitation
Objectives : To determine the cardiovascular and hemostatic effects of fire suppression and postexposure active cooling. Methods : Forty-four firefighters were evaluated before and after a 12-minute live-fire drill. Next, 50 firefighters performing the same drill were randomized to undergo postfire forearm immersion in 10[degrees]C water or standard rehabilitation. Results: In the first study, heart rate and core body temperature increased and serum C-reactive protein decreased but there were no significant changes in fibrinogen, sE-selectin, or sL-selectin. The second study demonstrated an increase...
Occupational exposure to particles and incidence of stroke
Objectives This paper aims to investigate the relation between occupational exposure to particles, particle size, and the incidence of ischemic and hemorrhagic stroke. Methods The cohort included all manual workers identified from the Swedish National Census in 1980, who were alive as of 1 January 1987. First time events of ischemic or hemorrhagic stroke during the period 1987–2005 were identified through linkage to the Hospital Discharge Register and the National Cause of Death Register. A job-exposure matrix for exposure to small (<1 µm) and large (>1 µm) particles was...
Risques accrus de crise cardiaque et d'AVC pour les travailleurs de l'amiante, selon une étude
Les travailleurs de l'amiante ont un « risque significativement accru » de mourir d'une crise cardiaque ou d'un accident vasculaire cérébral (AVC), selon les résultats d'une étude britannique parue mardi. « La mortalité par AVC et par cardiopathies coronariennes [principalement l'infarctus du myocarde] est beaucoup plus élevée pour les travailleurs de l'amiante que pour la population en général », expliquent des chercheurs du Health and Safety Laboratory, un laboratoire public britannique...

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