Occupational dermal exposure to nanoparticles and nano-enabled products

Part 2, exploration of exposure processes and methods of assessment
In the first of a series of two papers (Larese Filon et al., 2016), we focused our attention on identifying conditions or situations, i.e. a combination of nanoparticle physico-chemical properties, skin barrier integrity, and occupations with high prevalence of skin disease, which deserve further investigation. This second paper focuses on the broad question of dermal exposure assessment to nanoparticles and attempts to give an overview of the mechanisms of occupational dermal exposure to nanoparticles and nano-enabled products and explores feasibility and adequacy of various methods of quantifying dermal exposure to NOAA. We provide here a conceptual framework for screening, prioritization, and assessment of dermal exposure to NOAA in occupational settings, and integrate it into a proposed framework for risk assessment.

Source: Derk H. Brouwer, Suzanne Spaan, Martin Roff, Anne Sleeuwenhoek, Ilse Tuinman, Henk Goede, Birgit van Duuren-Stuurman, Francesca Larese Filon, Dhimiter Bello, John W. Cherrie. International Journal of Hygiene and Environmental Health, 2016.

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