Single and Combined Exposure to Zinc- and Copper-Containing Welding Fumes Lead to Asymptomatic Systemic Inflammation

Objective: Recently, it has been shown that exposure to welding fumes containing both zinc and copper leads to asymptomatic systemic inflammation in humans as shown by an increase of blood C-reactive protein. In the present study, it was investigated which metal is responsible for this effect.
Methods: Fifteen healthy male subjects were exposed under controlled conditions to welding fumes containing either zinc, or copper, or copper and zinc.
Results: For each exposure blood C-reactive protein increased.
Conclusions: Copper- and zinc-containing welding fumes are able to induce systemic inflammation.

Source: Markert, Agnieszka; Baumann, Ralf; Gerhards, Benjamin M.; Gube, Monika; Kossack, Veronika; Kraus, Thomas; Brand, Peter. Journal of Occupational & Environmental Medicine: February 2016, Volume 58, Issue 2, p. 127-132.

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