2012-12-01 12:00 - Messages

Silver Nanoparticles: NIOSH Seeks Information and Comment

Federal Register carried a notice from the National Institute for Occupational Health and Safety (NIOSH) requesting information and comments regarding silver nanoparticles. NIOSH has initiated an evaluation of the scientific data on silver nanoparticles (AgNPs) to ascertain the potential health risks to workers and to
identify gaps in knowledge so that appropriate laboratory and field research studies can be conducted. . . .

Source : http://www.nanolawreport.com/2012/12/articles/silver-nanoparticles-niosh-seeks-information-and-comment/#axzz2FWeaNAg8


Design optimization of hazardous substance storage facilities to minimize project risk

The storage of dangerous substances is a high risk procedure: a historical analysis revealed that 17% of the major accidents associated with the chemical industry are related to this process. When a storage facility is designed, the investment in safety is not always optimal. The safety measures that are applied are sometimes redundant or ill-maintained. One way to improve safety in a storage facility would be to take advantage of the fact that dividing the mass of dangerous substance results in less catastrophic accidents. In this paper, we present a new method for optimizing the design of storage plants and minimizing the risk by calculating the ideal number of tanks and improving the way in which money is invested in safety. This is achieved by redefining how to estimate risk and by applying the principles of mathematical optimization to quantitative risk analysis. The method is explained step by step. We also present two case studies and a validation of the method using risk analysis software and iso-risk curves.
Source : Bernechea EJ, Arnaldos Viger J. Safety Sci. 2013; 51(1): 49-62.  http://dx.doi.org/10.1016/j.ssci.2012.06.007

Reducing Exposure to Lead and Noise at Outdoor Firing Ranges

The National Institute for Occupational Safety and Health (NIOSH) recently published recommendations for reducing exposure to lead and noise at indoor firing ranges [NIOSH 2009]. However, workers and users of outdoor firing ranges may be exposed to similar hazards. This followup document examines exposures at these ranges and recommends steps to reduce such exposures.

Source : http://www.cdc.gov/niosh/docs/wp-solutions/2013-104/pdfs/2013-104.pdf


How Does an Occupational Neurologist Assess Welders and Steelworkers for a Manganese-Induced Movement Disorder?

Part II, will present a synopsis of the evaluation including blood and urine manganese and results from one magnetic resonance image and discuss and analyze the results. Limitations and conclusions will be presented. Part I, from an earlier JOEM issue, focused on the historical background and literature supporting parkinsonism and manganese exposure, both from mining and welding. Differential diagnosis, including radiological assessment and methods were discussed.

Source : Rutchik, Jonathan S., Zheng, Wei, Jiang, Yueming, Mo, Xuean, How Does an Occupational Neurologist Assess Welders and Steelworkers for a Manganese-Induced Movement Disorder? An International Team's Experiences in Guanxi, China, Part II, Journal of Occupational and Environmental Medicine, Vol. 54(12), Dec. 2012, p 1562–1564. http://dx.doi.org/10.1097/JOM.0b013e318216d01b

New study of nanoparticle skin penetration

As engineered nanoparticles (ENPs) become increasingly common in consumer products and the environment, concern over their possible effects on human health also rises. There is concern over the possible penetration of human skin by ENPs. "However, the evidence whether nanoparticles can infiltrate into underlying tissues is conflicting . . .  clarification of the issue is essential. . .."
With this in mind, Christopher. S.J. Campbell of Mango Business Solutions, L. Roderigo Contreras-Rojas, M. Begona Delgado-Charro, and Richard H. Guy, of the University of Bath Department of Pharmacy & Pharmacology have recently published a study "Objective assessment of nanoparticle disposition in mammalian skin after topical exposure" in the Journal of Controlled Release discussing the results of their attempts to measure the extent and depth that ENPs are able to penetrate the skin, in the case of this study the specially cleaned and prepared skin of a pig.

Source : http://www.nanolawreport.com/2012/10/articles/new-study-of-nanoparticle-skin-penetration/#axzz2BZZPPjwG

Christopher S.J. Campbell, L. Rodrigo Contreras-Rojas, M. Begoña Delgado-Charro, Richard H. Guy, Objective assessment of nanoparticle disposition in mammalian skin after topical exposure, Journal of Controlled Release, Vol. 162, Issue 1, 20 August 2012, p. 201-207. http://www.sciencedirect.com/science/article/pii/S016836591200524X

Silice cristalline : de la poussière à la maladie, il n'y a qu'un pas

Dossier TS : article publié dans le mensuel Travail et sécurité, n°732, octobre 2012

À l'heure actuelle, 270 000 salariés seraient exposés à la silice, dans une très grande diversité d'activités : extraction de roches, fabrication de prothèses dentaires, taille de pierre, verreries, fonderies, industries de la céramique et de la porcelaine, travaux publics...
La priorité en matière de prévention des risques professionnels doit être donnée à la protection collective, afin de réduire au maximum les émissions de poussières.

Source : http://www.inrs.fr/accueil/produits/mediatheque/doc/publications.html?refINRS=TS732page18

Study finds breast cancer link in industrial, trade sectors

A new study published November 19, 2012 in the Environmental Health Journal shows that a number of blue-collar jobs with exposure to chemicals may be increasing some women’s risk for breast cancer. The case control study selected 1,005 women with breast cancer and another 1,147 without the disease. Researchers found that  women who worked in jobs classified as “highly exposed” for a decade or more increased their breast cancer risk by 42 per cent.

Source : http://www.hazmatmag.com/news/study-finds-breast-cancer-link-in-industrial-trade-sectors/1001873756/x0slr4Mo48yy4W8srrqMt2M20/?link_source=aypr_HM&AF=&utm_source=HM&utm_medium=email&utm_campaign=HM-EN11222012&link_targ=DailyNews

James T Brophy, Margaret M Keith, Andrew Watterson, Robert Park, Michael Gilbertson, Eleanor Maticka-Tyndale, Matthias Beck, Hakam Abu-Zahra, Kenneth Schneider, Abraham Reinhartz, Robert DeMatteo and Isaac Luginaah, Breast cancer risk in relation to occupations with exposure to carcinogens and endocrine disruptors: a Canadian case--control study, Environmental Health 2012, 11:87 http://dx.doi.org/10.1186/1476-069X-11-87


Acute Cardiovascular Effects of Firefighting and Active Cooling During Rehabilitation

Objectives: To determine the cardiovascular and hemostatic effects of fire suppression and postexposure active cooling. Methods: Forty-four firefighters were evaluated before and after a 12-minute live-fire drill. Next, 50 firefighters performing the same drill were randomized to undergo postfire forearm immersion in 10[degrees]C water or standard rehabilitation. Results: In the first study, heart rate and core body temperature increased and serum C-reactive protein decreased but there were no significant changes in fibrinogen, sE-selectin, or sL-selectin. The second study demonstrated an increase in blood coagulability, leukocyte count, factors VIII and X, cortisol, and glucose, and a decrease in plasminogen and sP-selectin. Active cooling reduced mean core temperature, heart rate, and leukocyte count. Conclusions: Live-fire exposure increased core temperature, heart rate, coagulability, and leukocyte count; all except coagulability were reduced by active cooling.

Source : Burgess, Jefferey L. MD, MS, MPH; Duncan, Michael D. BA; Hu, Chengcheng PhD; Littau, Sally R. BS; Caseman, Delayne MPH; Kurzius-Spencer, Margaret MS, MPH; Davis-Gorman, Grace BS; McDonagh, Paul F., Acute Cardiovascular Effects of Firefighting and Active Cooling During Rehabilitation, Journal of Occupational & Environmental Medicine. 54(11):1413-1420, November 2012. http://dx.doi.org/10.1097/JOM.0b013e3182619018

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